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基于多导睡眠图记录的睡眠呼吸暂停事件识别:一种大规模多通道机器学习方法。

Sleep Apnea Events Recognition Based on Polysomnographic Recordings: A Large-Scale Multi-Channel Machine Learning approach.

作者信息

La Porta Nicolo, Scafa Stefano, Papandrea Michela, Molinari Filippo, Puiatti Alessandro

机构信息

Faculty of InformaticsUniversità della Svizzera Italiana (USI) 6900 Lugano Switzerland.

Institute of Information Systems and Networking (ISIN)University of Applies Sciences and Arts of Southern Switzerland (SUPSI) 6962 Lugano-Viganello Switzerland.

出版信息

IEEE Open J Eng Med Biol. 2024 Nov 28;6:202-211. doi: 10.1109/OJEMB.2024.3508477. eCollection 2025.

DOI:10.1109/OJEMB.2024.3508477
PMID:39698117
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11655111/
Abstract

The gold standard for detecting the presence of apneic events is a time and effort-consuming manual evaluation of type I polysomnographic recordings by experts, often not error-free. Such acquisition protocol requires dedicated facilities resulting in high costs and long waiting lists. The usage of artificial intelligence models assists the clinician's evaluation overcoming the aforementioned limitations and increasing healthcare quality. The present work proposes a machine learning-based approach for automatically recognizing apneic events in subjects affected by sleep apnea-hypopnea syndrome. It embraces a vast and diverse pool of subjects, the Wisconsin Sleep Cohort (WSC) database. An overall accuracy of 87.2[Formula: see text]1.8% is reached for the event detection task, significantly higher than other works in literature performed over the same dataset. The distinction between different types of apnea was also studied, obtaining an overall accuracy of 62.9[Formula: see text]4.1%. The proposed approach for sleep apnea events recognition, validated over a wide pool of subjects, enlarges the landscape of possibilities for sleep apnea events recognition, identifying a subset of signals that improves State-of-the-art performance and guarantees simple interpretation.

摘要

检测呼吸暂停事件存在的金标准是由专家对I型多导睡眠图记录进行耗时费力的人工评估,且往往并非完全无误。这样的采集方案需要专门的设备,导致成本高昂且等待名单很长。人工智能模型的使用有助于临床医生的评估,克服了上述局限性并提高了医疗质量。本研究提出了一种基于机器学习的方法,用于自动识别受睡眠呼吸暂停低通气综合征影响的受试者中的呼吸暂停事件。它采用了大量不同的受试者群体,即威斯康星睡眠队列(WSC)数据库。对于事件检测任务,总体准确率达到了87.2±1.8%,显著高于在同一数据集上进行的其他文献研究。还研究了不同类型呼吸暂停之间的区分,总体准确率为62.9±4.1%。所提出的睡眠呼吸暂停事件识别方法在大量受试者中得到了验证,拓宽了睡眠呼吸暂停事件识别的可能性范围,识别出了一组能提高现有技术水平性能并保证易于解释的信号子集。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/658d98368f9e/lapor3-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/a540935aa2a4/lapor1-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/0b2adcc8f6b5/lapor2-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/658d98368f9e/lapor3-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/a540935aa2a4/lapor1-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/0b2adcc8f6b5/lapor2-3508477.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0fa/11655111/658d98368f9e/lapor3-3508477.jpg

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本文引用的文献

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Duration of respiratory events in obstructive sleep apnea: Factors influencing the duration of respiratory events.阻塞性睡眠呼吸暂停中呼吸事件的持续时间:影响呼吸事件持续时间的因素。
Sleep Med Rev. 2023 Apr;68:101729. doi: 10.1016/j.smrv.2022.101729. Epub 2022 Dec 9.
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Duration of respiratory events in obstructive sleep apnea: In search of paradoxical results.阻塞性睡眠呼吸暂停中呼吸事件的持续时间:探寻矛盾结果
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A review of automated sleep disorder detection.
自动睡眠障碍检测综述。
Comput Biol Med. 2022 Nov;150:106100. doi: 10.1016/j.compbiomed.2022.106100. Epub 2022 Sep 16.
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Stop Explaining Black Box Machine Learning Models for High Stakes Decisions and Use Interpretable Models Instead.停止为高风险决策解释黑箱机器学习模型,转而使用可解释模型。
Nat Mach Intell. 2019 May;1(5):206-215. doi: 10.1038/s42256-019-0048-x. Epub 2019 May 13.
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Re-focusing explainability in medicine.重新聚焦医学中的可解释性。
Digit Health. 2022 Feb 11;8:20552076221074488. doi: 10.1177/20552076221074488. eCollection 2022 Jan-Dec.
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Sleep apnoea and ischaemic stroke: current knowledge and future directions.睡眠呼吸暂停与缺血性脑卒中:现有认识与未来方向。
Lancet Neurol. 2022 Jan;21(1):78-88. doi: 10.1016/S1474-4422(21)00321-5.
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A Survey on Recent Advances in Machine Learning Based Sleep Apnea Detection Systems.基于机器学习的睡眠呼吸暂停检测系统的最新进展综述
Healthcare (Basel). 2021 Jul 20;9(7):914. doi: 10.3390/healthcare9070914.
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The design of RIP belts impacts the reliability and quality of the measured respiratory signals.RIP 带的设计会影响所测量呼吸信号的可靠性和质量。
Sleep Breath. 2021 Sep;25(3):1535-1541. doi: 10.1007/s11325-020-02268-x. Epub 2021 Jan 7.
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Digital oximetry biomarkers for assessing respiratory function: standards of measurement, physiological interpretation, and clinical use.用于评估呼吸功能的数字血氧测定生物标志物:测量标准、生理学解释及临床应用
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