巴西一个流行地区皮肤利什曼病公共卫生实验室网络的评估。
Evaluation of the public health laboratory network for tegumentary leishmaniasis in an endemic area of Brazil.
作者信息
Medeiros Fernanda Alvarenga Cardoso, Souza Filho Job Alves, Pimentel Maria Inês Fernandes, Reis Ilka Afonso, Menezes-Souza Daniel, Silva Aline Fagundes da, Marcelino Andreza Pain
机构信息
Universidade Federal de Minas Gerais, Faculdade de Medicina, Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Belo Horizonte, Minas Gerais, Brazil.
Fundação Ezequiel Dias, Instituto Octávio Magalhães, Serviço de Doenças Parasitárias da Divisão de Epidemiologia e Controle de Doenças, Belo Horizonte, Minas Gerais, Brazil.
出版信息
Rev Inst Med Trop Sao Paulo. 2024 Dec 6;66:e70. doi: 10.1590/S1678-9946202466070. eCollection 2024.
Diagnostic networks ensure efficiency in disease diagnosis. A descriptive study evaluated the network of public health laboratories (NPHL) in Minas Gerais State, Brazil, using diagnostic results for tegumentary leishmaniasis (TL) from the laboratory management system in 2017-2020. Out of 1,369 individuals analyzed, 704 (51.4%) cases of TL were confirmed, with 610 (86.7%) by direct parasitological examination (DPE) and 94 (13.4%) by polymerase chain reaction (PCR). Notably, 25.3% of cases with DPE-negative results were PCR-positive. Consecutive diagnostic tests enhanced diagnosis of TL. NPHL-MG is a promising model for expanding similar networks and improving disease control.
诊断网络可确保疾病诊断的效率。一项描述性研究利用2017年至2020年实验室管理系统中皮肤利什曼病（TL）的诊断结果，对巴西米纳斯吉拉斯州的公共卫生实验室网络（NPHL）进行了评估。在分析的1369名个体中，确诊了704例（51.4%）TL病例，其中610例（86.7%）通过直接寄生虫学检查（DPE）确诊，94例（13.4%）通过聚合酶链反应（PCR）确诊。值得注意的是，DPE结果为阴性的病例中有25.3%通过PCR检测呈阳性。连续的诊断测试提高了TL的诊断率。NPHL-MG是扩展类似网络和改善疾病控制的一个有前景的模式。
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