Vertigan Anne E, Haines Jemma
Speech Pathology Department, John Hunter Hospital, Newcastle, New South Wales, Australia; Centre for Asthma and Breathing, Hunter Medical Research Institute, Newcastle, New South Wales, Australia; School of Medicine and Public Health, College of Health and Wellbeing, University of Newcastle, Newcastle, New South Wales, Australia.
Faculty of Biology, Medicine and Health, School of Biological Sciences, Division of Infection, Immunity & Respiratory Medicine, The University of Manchester, Manchester, United Kingdom; NIHR-Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom.
J Allergy Clin Immunol Pract. 2025 Mar;13(3):480-488. doi: 10.1016/j.jaip.2024.12.012. Epub 2024 Dec 17.
Although cough is a protective reflex, it can occur in the absence of any physical need to clear the airway. In chronic cough, cough can be triggered by innocuous stimuli and persist despite medical treatment. Nonpharmacological interventions such as cough control therapy, provided by speech pathologists, have gained popularity in recent years. Intervention targets refractory or unexplained chronic cough, and efficacy has been studied in randomized controlled trials. Key elements of cough control therapy include education, anticipation, and control of the urge to cough, reducing laryngeal irritation and psychoeducational counseling. Our understanding of the mechanisms behind the success of nonpharmacological treatment is developing. It is likely the mechanisms of action are multifactorial across peripheral, central, and higher cortical regions. Nonpharmacological cough control therapy interventions are now included in international cough guidelines. However, approach to service delivery is not standardized and varies between regions and countries.
尽管咳嗽是一种保护性反射,但在没有任何清除气道的生理需求时也可能发生。在慢性咳嗽中,咳嗽可由无害刺激引发,且尽管接受了治疗仍会持续。近年来,言语病理学家提供的诸如咳嗽控制疗法等非药物干预措施越来越受欢迎。该干预针对难治性或不明原因的慢性咳嗽,其疗效已在随机对照试验中得到研究。咳嗽控制疗法的关键要素包括教育、预期以及对咳嗽冲动的控制、减少喉部刺激和心理教育咨询。我们对非药物治疗成功背后机制的理解正在不断发展。其作用机制可能在外周、中枢和更高皮层区域是多因素的。非药物咳嗽控制疗法干预措施现已纳入国际咳嗽指南。然而,服务提供方式并不标准化,且在不同地区和国家有所不同。