Islami Isnaini Nur, Muhamadi Amar Ma'ruf Irfan, Wibowo Wahyu Edy, Putranto Aloysius Mario Yudi, Sudarmaji Arief, Djuita Fielda, Pawiro Supriyanto Ardjo
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, West Java, 16424 Indonesia and Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital Central, Jakarta, Indonesia.
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, West Java, Indonesia.
J Appl Clin Med Phys. 2025 Apr;26(4):e14607. doi: 10.1002/acm2.14607. Epub 2024 Dec 20.
The goal of this study was to assess the feasibility of a cost-effective prototype of a laser-based respiratory motion detection system utilizing a Leuze LDS for breath monitoring through calibration and volunteer tests.
This study was performed using the Anzai AZ-773 V and computerized imaging reference systems (CIRS) motion phantoms for calibration tests. The calibration of the laser-based respiratory motion detection system involved spatial accuracy testing, amplitude calibration, and temporal accuracy. Volunteer testing was conducted on eight volunteers at the inferior end of the sternum and the abdomen area. The accuracy of the data recorded by the laser-based respiratory motion detection system was validated against established clinical reference tracking systems namely real-time position management (RPM) and Anzai AZ-733 V system.
Calibration with an Anzai AZ-773 V and CIRS phantoms demonstrated an average error of 1.17% ± 0.64% and an average amplitude calibration correlation coefficient of 0.975 ± 0.004. Volunteer tests, compared to the Anzai AZ-733 V clinical system and RPM system, revealed average correlation coefficients for deep inspiration breath-hold are 0.931 ± 0.02 and 0.936 ± 0.03, respectively, and for free breathing are 0.85 ± 0.07 and 0.77 ± 0.1, respectively.
Overall, the data suggest that the in-house laser-based respiratory motion detection system performed well, with an error percentage below 10%. A reasonably good correlation coefficient was obtained, indicating that the readings obtained from the laser system are consistent with those set on the phantom and clinical respiratory motion detection systems. Although promising through the calibration process and volunteer tests, further studies are required to generate trigger data linked directly to computerized tomography and linear accelerator facilities, thereby advancing the clinical viability of this innovative laser-based respiratory motion detection system.
本研究的目的是通过校准和志愿者测试，评估一种利用劳易测激光位移传感器（Leuze LDS）进行呼吸监测的具有成本效益的激光呼吸运动检测系统原型的可行性。
本研究使用安斋AZ - 773V和计算机成像参考系统（CIRS）运动体模进行校准测试。基于激光的呼吸运动检测系统的校准包括空间精度测试、幅度校准和时间精度测试。在八名志愿者的胸骨下端和腹部区域进行了志愿者测试。基于激光的呼吸运动检测系统记录的数据的准确性，通过既定的临床参考跟踪系统即实时位置管理（RPM）和安斋AZ - 733V系统进行了验证。
使用安斋AZ - 773V和CIRS体模进行校准，平均误差为1.17%±0.64%，平均幅度校准相关系数为0.975±0.004。与安斋AZ - 733V临床系统和RPM系统相比，志愿者测试显示，深吸气屏气时的平均相关系数分别为0.931±0.02和0.936±0.03，自由呼吸时分别为0.85±0.07和0.77±0.1。
总体而言，数据表明内部基于激光的呼吸运动检测系统表现良好，误差百分比低于10%。获得了合理良好的相关系数，表明从激光系统获得的读数与体模和临床呼吸运动检测系统上设置的读数一致。尽管通过校准过程和志愿者测试很有前景，但仍需要进一步研究以生成直接与计算机断层扫描和直线加速器设备相关的触发数据，从而提高这种创新的基于激光的呼吸运动检测系统的临床可行性。
