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胃食管反流的管理

Management of gastro-oesophageal reflux.

作者信息

Carré I J

出版信息

Arch Dis Child. 1985 Jan;60(1):71-5. doi: 10.1136/adc.60.1.71.

Abstract

Parental reassurance and thickened feeds are the only requirements in the management of infants with reflux when this is the sole detectable gastro-oesophageal abnormality. In view of the strong propensity for spontaneous clinical resolution and the excellent results achieved by conservative management, infants with reflux due to a partial thoracic stomach (hiatal hernia) uncomplicated by a stricture should be treated in the first instance by postural therapy, with or without thickened feeds and supplements of antacids, domperidone, and cimetidine. Those showing no response after an adequate period of conservative treatment should have an antireflux operation. The Belsey MK IV type of fundoplication is preferred. Only an exceptional patient will require to be treated surgically before 12 months of age. The same surgical antireflux procedure, combined with oesophageal dilatations as necessary, is the treatment of choice for patients with a partial thoracic stomach complicated by a reflux oesophageal stricture. A similar treatment regimen should be followed for patients with reflux after repair of an oesophageal atresia. Surgical correction is mandatory for all infants with reflux due to a large combined hiatal hernia.

摘要

当反流是唯一可检测到的胃食管异常时,安抚家长和增加奶液黏稠度是管理反流婴儿的唯一要求。鉴于自发临床缓解的强烈倾向以及保守治疗取得的良好效果,对于因部分胸胃(食管裂孔疝)导致的反流且无狭窄并发症的婴儿,首先应采用体位疗法进行治疗,可加用或不加用增稠奶液以及使用抗酸剂、多潘立酮和西咪替丁补充剂。经过足够疗程的保守治疗后无反应的患儿应进行抗反流手术。首选Belsey MK IV型胃底折叠术。只有极少数患者需要在12个月龄之前接受手术治疗。对于因部分胸胃合并反流性食管狭窄的患者,同样的手术抗反流程序并根据需要进行食管扩张是首选治疗方法。食管闭锁修复术后反流的患者应遵循类似的治疗方案。对于所有因巨大复合型食管裂孔疝导致反流的婴儿,手术矫正必不可少。

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