Spitz L, Roth K, Kiely E M, Brereton R J, Drake D P, Milla P J
Department of Surgery, Hospital for Sick Children, London.
Arch Dis Child. 1993 Mar;68(3):347-51. doi: 10.1136/adc.68.3.347.
One hundred and seventy six children with severe mental retardation underwent a fundoplication for considerable gastro-oesophageal reflux. There were six 'early' (3%) deaths and five 'late' deaths. Major complications developed in 17 (10%) children whereas 86 (49%) had 'minor' complications. A revision operation was required in 27 patients. Overall 142 (81%) children achieved a good result. In spite of the high complication rate and the need for a secondary operation in 15% of the patients, the quality of life for these children and their parents and carers is greatly improved by antireflux surgery.
176名患有严重智力障碍的儿童因严重胃食管反流接受了胃底折叠术。有6例“早期”(3%)死亡和5例“晚期”死亡。17名(10%)儿童出现了严重并发症,而86名(49%)有“轻微”并发症。27例患者需要进行翻修手术。总体而言,142名(81%)儿童取得了良好效果。尽管并发症发生率高且15%的患者需要二次手术,但抗反流手术极大地改善了这些儿童及其父母和护理人员的生活质量。