Gibson T, Clark B
Ann Rheum Dis. 1985 Jan;44(1):27-9. doi: 10.1136/ard.44.1.27.
The usefulness of anti-inflammatory drugs in rheumatoid arthritis (RA) is beyond dispute. The role of simple analgesics is less clear and has been disputed. A survey of 21 rheumatologists indicated that a majority sometimes supplemented anti-inflammatory treatment of RA with simple analgesics. A random sample of 120 RA patients treated by the same doctors revealed that 47% ranked pain relief as the most desirable objective of their treatment and 54% were taking analgesics regularly. Of those receiving analgesics as well as non-steroidal anti-inflammatory drugs 48% considered the former to be the more effective preparations. Almost half the patients on analgesics were taking drugs without the knowledge of the rheumatologists, who may have underestimated their patients' desire for pain relief.
抗炎药物在类风湿性关节炎(RA)中的效用无可争议。单纯镇痛药的作用则不太明确,且一直存在争议。一项针对21位风湿病学家的调查表明,大多数人有时会用单纯镇痛药辅助类风湿性关节炎的抗炎治疗。由这些医生治疗的120名类风湿性关节炎患者的随机样本显示,47%的患者将缓解疼痛列为治疗最期望达到的目标,54%的患者在定期服用镇痛药。在同时服用镇痛药和非甾体抗炎药的患者中,48%的人认为前者是更有效的制剂。几乎一半服用镇痛药的患者是在风湿病学家不知情的情况下用药的,而这些医生可能低估了患者缓解疼痛的需求。