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侵袭性念珠菌病

Invasive Candidiasis.

作者信息

Schroeder Julia A, Wilson Cameron M, Pappas Peter G

机构信息

The University of Alabama at Birmingham, 1900 University Boulevard, 223 THT, Birmingham, AL 35294, USA.

The University of Alabama at Birmingham, 1900 University Boulevard, 223 THT, Birmingham, AL 35294, USA.

出版信息

Infect Dis Clin North Am. 2025 Mar;39(1):93-119. doi: 10.1016/j.idc.2024.11.007. Epub 2024 Dec 20.

Abstract

Invasive candidiasis (IC) is a term that refers to a group of infectious syndromes caused by a variety of Candida species, 6 of which cause the vast majority of cases globally. Candidemia is probably the most commonly recognized syndrome associated with IC; however, Candida species can cause invasive infection of any organ, especially visceral organs, vasculature, bones and joints, eyes, and central nervous system. The optimal use of these newer diagnostics coupled with a thoughtful clinical assessment of at-risk patients and the judicious use of effective antifungal therapy is a key to achieving good antifungal stewardship and improved patient outcomes.

摘要

侵袭性念珠菌病(IC)是一个术语,指由多种念珠菌属引起的一组感染综合征,其中6种在全球导致了绝大多数病例。念珠菌血症可能是与IC相关的最常见的公认综合征;然而,念珠菌属可引起任何器官的侵袭性感染,尤其是内脏器官、脉管系统、骨骼和关节、眼睛及中枢神经系统。合理使用这些新型诊断方法,结合对高危患者进行全面的临床评估以及明智地使用有效的抗真菌治疗,是实现良好的抗真菌管理和改善患者预后的关键。

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