Veenstra Coen, Kolader Marion, Matamoros Sébastien, Sigaloff Kim
Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Ann Clin Microbiol Antimicrob. 2024 Dec 20;23(1):109. doi: 10.1186/s12941-024-00764-6.
Non-O1/non-O139 Vibrio cholerae (NOVC) strains are a distinct group of Vibrio cholerae that do not cause epidemic cholera. NOVC infections usually cause mild forms of gastroenteritis, and rarely severe (extra)intestinal infections, mostly affecting immunocompromised patients. Here, we describe the clinical course of a patient with NOVC bacteremia causing multiple liver abscesses, after drinking from a freshwater well in a non-coastal area. This case highlights the potential of a V. cholerae strain, that is phylogenetically distinct from the current pandemic cholera strain, to cause severe extra-intestinal infections, including liver abscesses.
非O1/非O139霍乱弧菌(NOVC)菌株是霍乱弧菌的一个独特类别,不会引发霍乱流行。NOVC感染通常导致轻度肠胃炎,极少引发严重的(肠道外)感染,主要影响免疫功能低下的患者。在此,我们描述了一名患者的临床病程,该患者在非沿海地区饮用淡水井中的水后,发生了由NOVC菌血症导致的多发性肝脓肿。此病例凸显了一种在系统发育上与当前大流行霍乱菌株不同的霍乱弧菌菌株引发包括肝脓肿在内的严重肠道外感染的可能性。