He Meiheng, Wang Lili, Xu Ding, Liu Ying, Zhu Xiangru, Zhu Dong, Yang Suyong
School of Psychology, Northwest Normal University, Lanzhou, China.
School of Psychology, Shanghai University of Sport, Shanghai, China.
Scand J Med Sci Sports. 2024 Dec;34(12):e70006. doi: 10.1111/sms.70006.
Acute high-intensity interval training (HIIT) has cognitive benefits in individuals with methamphetamine use disorder (MUD), yet it remains largely unknown the benefits of long-term HIIT on emotional conflict control and its neural mechanism in individuals with MUD. The current study conducted a 36-week low-volume HIIT intervention to investigate the effects of HIIT on emotional conflict control in males with MUD and their prefrontal cortex (PFC) activation. This study was a sub-study of the Study for Rehabilitation Training Model Construction and Training Effect of High Intensity Compound Exercise Prescription. Forty males with MUD (31.50 ± 4.33 years) were randomly assigned to the HIIT group and control group. The HIIT group received a 36-week low-volume HIIT intervention, while the control group maintained daily physical exercise. The emotional conflict task (emotional face-word Stroop task) with functional near-infrared spectroscopy (fNIRS) recording and subjective craving test were performed before and after the intervention. The results showed that the HIIT intervention reduced the emotional conflict and increased cortical activations of right dorsolateral PFC (dlPFC) and right ventrolateral PFC (vlPFC). More importantly, the HIIT-induced decreased emotional conflict was associated significantly with increased right vlPFC activation. In addition, subjective craving was also reduced after HIIT intervention. While the control group showed significant changes in neither brain activation nor the craving. These findings suggest that long-term low-volume HIIT can improve PFC activation, promote emotional conflict control, and reduce subjective craving in males with MUD. HIIT seems to be an effective method of withdrawal rehabilitation for males with MUD.
急性高强度间歇训练（HIIT）对甲基苯丙胺使用障碍（MUD）个体具有认知益处，但长期HIIT对MUD个体情绪冲突控制及其神经机制的益处仍 largely unknown。本研究进行了为期36周的低容量HIIT干预，以调查HIIT对MUD男性情绪冲突控制及其前额叶皮质（PFC）激活的影响。本研究是高强度复合运动处方康复训练模型构建与训练效果研究的子研究。40名MUD男性（31.50±4.33岁）被随机分配到HIIT组和对照组。HIIT组接受为期36周的低容量HIIT干预，而对照组维持日常体育锻炼。在干预前后进行了功能性近红外光谱（fNIRS）记录的情绪冲突任务（情绪面孔-单词Stroop任务）和主观渴望测试。结果表明，HIIT干预减少了情绪冲突，并增加了右侧背外侧PFC（dlPFC）和右侧腹外侧PFC（vlPFC）的皮质激活。更重要的是，HIIT引起的情绪冲突减少与右侧vlPFC激活增加显著相关。此外，HIIT干预后主观渴望也降低了。而对照组在大脑激活和渴望方面均无显著变化。这些发现表明，长期低容量HIIT可以改善MUD男性的PFC激活，促进情绪冲突控制，并减少主观渴望。HIIT似乎是MUD男性戒断康复的有效方法。
