Zhao Li-Yuan, Zhang Guang-Fen, Yang Jian-Jun, Diao Yu-Gang, Hashimoto Kenji
Department of Anesthesiology, Pain and Perioperative Medicine, The first Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China.
Brain Res Bull. 2025 Jan;220:111175. doi: 10.1016/j.brainresbull.2024.111175. Epub 2024 Dec 20.
Chronic pain is commonly recognized as a distressing symptom or a standalone disease, with over half of those affected experiencing cognitive impairment, which significantly impacts their quality of life. Despite a recent surge in literature on cognitive impairment associated with chronic pain, a comprehensive bibliometric analysis in this field has yet to be conducted. In this study, we performed a bibliometric analysis on this topic. We retrieved English-language publications on chronic pain and cognitive impairment from 2000 to 2024 using the Web of Science Core Collection database. These publications were visually analyzed using tools such as VOSviewer, CiteSpace, and the R package "bibliometrix." We identified 1656 publications from 72 countries/regions across 722 journals on the topic of chronic pain and cognitive impairment. Publication numbers showed a steady increase, peaking in 2022. The United States led in contributions, with Harvard Medical School emerging as the most prominent institution involved. The journal Pain was the most prolific and frequently co-cited in this area. Among the authors, Stefan Duschek was the most productive, while Frederick Wolfe was the most frequently co-cited. Key research areas include investigating the bidirectional long-term effects between chronic pain and cognitive impairment and exploring the mechanisms underlying cognitive changes associated with chronic pain. In conclusion, this study highlights a global surge in research on cognitive impairment related to chronic pain. Emerging hotspots and future research trends point towards brain imaging mechanisms and neuronal circuit-mediated processes.
慢性疼痛通常被认为是一种令人痛苦的症状或一种独立的疾病，超过一半的患者存在认知障碍，这对他们的生活质量产生了重大影响。尽管最近关于慢性疼痛相关认知障碍的文献激增，但该领域尚未进行全面的文献计量分析。在本研究中，我们对这一主题进行了文献计量分析。我们使用科学网核心合集数据库检索了2000年至2024年期间关于慢性疼痛和认知障碍的英文出版物。使用VOSviewer、CiteSpace和R包“bibliometrix”等工具对这些出版物进行了可视化分析。我们确定了来自72个国家/地区、发表在722种期刊上的1656篇关于慢性疼痛和认知障碍主题的出版物。发表数量呈稳步上升趋势，在2022年达到峰值。美国在贡献方面领先，哈佛医学院是涉及的最突出机构。《疼痛》杂志是该领域发表文章最多且被频繁共同引用的期刊。在作者中，斯特凡·杜舍克发表文章最多，而弗雷德里克·沃尔夫被共同引用的频率最高。关键研究领域包括调查慢性疼痛与认知障碍之间的双向长期影响，以及探索与慢性疼痛相关的认知变化的潜在机制。总之，本研究突出了全球范围内对慢性疼痛相关认知障碍研究的激增。新兴热点和未来研究趋势指向脑成像机制和神经元回路介导的过程。
