Rowe E S
Biochim Biophys Acta. 1985 Mar 14;813(2):321-30. doi: 10.1016/0005-2736(85)90248-2.
The gel-to-fluid phase transitions of several phosphatidylethanolamines (PE's) and phosphatidylcholines (PC's) have been investigated in the presence of three short-chain alcohols. The effects of the alcohols on the thermodynamic reversibility of these transitions was studied and it was found that the transitions for PC's are not thermodynamically reversible at relatively high alcohol concentrations. The PE transitions are thermodynamically reversible for all alcohol concentrations, and the PE's do not exhibit the biphasic effects of alcohol on the transition temperature previously reported for the PC's (Rowe, E.S. (1983) Biochemistry 22, 3299-3305). The biphasic transition temperature effects and the thermodynamic irreversibility of PC transitions at high alcohol concentrations appear to be correlated with the induction of a fully interdigitated gel phase recently reported in the literature (Simon, S.A. and McIntosh, T.J. (1984) Biochim. Biophys. Acta 773, 169-172). The biological significance of these findings is discussed.
在三种短链醇存在的情况下，对几种磷脂酰乙醇胺（PE）和磷脂酰胆碱（PC）的凝胶-流体相变进行了研究。研究了醇对这些相变热力学可逆性的影响，发现PC在相对较高的醇浓度下相变不是热力学可逆的。对于所有醇浓度，PE相变都是热力学可逆的，并且PE没有表现出先前报道的PC中醇对相变温度的双相效应（Rowe，E.S.（1983年）《生物化学》22卷，3299 - 3305页）。PC在高醇浓度下的双相相变温度效应和热力学不可逆性似乎与文献中最近报道的完全交错凝胶相的诱导有关（Simon，S.A.和McIntosh，T.J.（1984年）《生物化学与生物物理学报》773卷，169 - 172页）。讨论了这些发现的生物学意义。
