• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Characterization of two molecular species GD3 ganglioside from bovine buttermilk.

作者信息

Hauttecoeur B, Sonnino S, Ghidoni R

出版信息

Biochim Biophys Acta. 1985 Feb 8;833(2):303-7. doi: 10.1016/0005-2760(85)90202-4.

DOI:10.1016/0005-2760(85)90202-4
PMID:3970956
Abstract

Two gangliosides, representing 85% of total lipid-bound sialic acid, have been isolated from bovine buttermilk and characterized. Both contained long-chain base, glucose, galactose and sialic acid in the molar ratio 1:1:1:2, and gave, upon sialidase treatment, a neutral glycolipid, characterized as lactosylceramide. Partial acid hydrolysis, permethylation analysis and chromium trioxide oxidation indicated their basic oligosaccharide portion to be NeuAc alpha 2----8NeuAc alpha 2----3Gal beta 1----4Glc. The difference between the two forms was exclusively in the ceramide moiety of the molecule, one containing mainly long-chain (C22-C25) fatty acids and an equimolar proportion of C16 and C18 long-chain bases, and the other mainly palmitic acid and C18 long-chain base.

摘要

相似文献

1
Characterization of two molecular species GD3 ganglioside from bovine buttermilk.
Biochim Biophys Acta. 1985 Feb 8;833(2):303-7. doi: 10.1016/0005-2760(85)90202-4.
2
Gangliosides of bovine buttermilk. Isolation and characterization of a novel monosialoganglioside with a new branching structure.牛乳清中的神经节苷脂。一种具有新分支结构的新型单唾液酸神经节苷脂的分离与鉴定。
J Biol Chem. 1986 Apr 25;261(12):5625-30.
3
Glycolipid composition of human cataractous lenses. Characterization of Lewisx glycolipids.人白内障晶状体的糖脂组成。Lewisx糖脂的特性
J Biol Chem. 1994 Jan 28;269(4):2667-75.
4
Isolation and characterization of a novel phytosphingosine-containing GM2 ganglioside from mullet roe (Mugil cephalus).
J Biol Chem. 1984 Jul 25;259(14):8980-5.
5
Glycosphingolipids in Bomirski transplantable melanomas in hamsters.仓鼠博米尔斯基可移植黑色素瘤中的糖鞘脂
Cancer Res. 1989 Dec 15;49(24 Pt 1):7051-6.
6
Studies on the glycosphingolipids of the starfish, Asterina pectinifera. II. Isolation and characterization of a novel ganglioside with an internal sialic acid residue.多棘海盘车糖鞘脂的研究。II. 一种含有内部唾液酸残基的新型神经节苷脂的分离与鉴定。
J Biochem. 1979 Aug;86(2):289-300. doi: 10.1093/oxfordjournals.jbchem.a132526.
7
Characterization of gangliosides of porcine erythrocyte membranes: occurrence of ganglioside GD3 as major ganglioside.猪红细胞膜神经节苷脂的特性：以神经节苷脂GD3作为主要神经节苷脂的存在情况。
Lipids. 1985 Sep;20(9):588-93. doi: 10.1007/BF02534284.
8
Occurrence of tumor-associated ganglioside antigens with Hanganutziu-Deicher antigenic activity on human melanomas.人类黑色素瘤上具有汉努齐乌-戴歇尔抗原活性的肿瘤相关神经节苷脂抗原的出现情况。
Jpn J Cancer Res. 1987 Jun;78(6):614-20.
9
Isolation and characterization of gangliosides from Theileria sergenti.瑟氏泰勒虫神经节苷脂的分离与鉴定
J Vet Med Sci. 1996 Nov;58(11):1099-105. doi: 10.1292/jvms.58.11_1099.
10
Isolation and characterization of major gangliosides from frog liver.青蛙肝脏主要神经节苷脂的分离与鉴定
J Biochem. 1987 Oct;102(4):923-32. doi: 10.1093/oxfordjournals.jbchem.a122133.

引用本文的文献

1
Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.鉴定大肠杆菌不耐热肠毒素 LT-IIc 的神经节苷脂识别特性。
Glycobiology. 2022 Apr 21;32(5):391-403. doi: 10.1093/glycob/cwab133.
2
Apoptosis of human breast carcinoma cells in the presence of disialosyl gangliosides: II. Treatment of SKBR3 cells with GD3 and GD1b gangliosides.在二唾液酸神经节苷脂存在下人类乳腺癌细胞的凋亡：II. 用GD3和GD1b神经节苷脂处理SKBR3细胞。
Glycoconj J. 2004;20(5):319-30. doi: 10.1023/B:GLYC.0000033628.39302.ae.
3
Chemical and enzymatic transacylation of amide-linked FA of buttermilk gangliosides.
酪乳神经节苷脂酰胺连接脂肪酸的化学和酶促转酰基作用。
Lipids. 2003 Aug;38(8):855-64. doi: 10.1007/s11745-003-1136-3.
4
Changes of the ganglioside pattern and content in human fibroblasts by high density cell population subculture progression.高密度细胞群体传代培养过程中人类成纤维细胞神经节苷脂模式和含量的变化。
Glycoconj J. 2002 Mar;19(3):181-6. doi: 10.1023/A:1024249707516.
5
Bovine milk gangliosides: changes in ceramide moiety with stage of lactation.牛乳神经节苷脂：神经酰胺部分随泌乳阶段的变化
Lipids. 2001 Mar;36(3):291-8. doi: 10.1007/s11745-001-0720-x.
6
A rapid method for the preparation of ganglioside Glac2 (GD3).一种制备神经节苷脂Glac2（GD3）的快速方法。
Lipids. 1994 May;29(5):365-8. doi: 10.1007/BF02537191.
7
Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses.唾液酸糖蛋白可抑制轮状病毒的体外和体内复制。
J Clin Invest. 1987 Jan;79(1):148-54. doi: 10.1172/JCI112775.
8
Isolation and characterization of ganglioside 9-O-acetyl-GD3 from bovine buttermilk.
Lipids. 1989 Aug;24(8):680-4. doi: 10.1007/BF02535204.