Williams K M, Iacono W G, Remick R A
Biol Psychiatry. 1985 Feb;20(2):158-62. doi: 10.1016/0006-3223(85)90075-7.
To determine whether subgroups of depressed patients could be differentiated on the basis of electrodermal activity (EDA), the skin conductance of 36 depressed patients was recorded for two experimental conditions. In the first condition, subjects heard 10 85-dB tones after receiving instructions that were intended to relax the patients. In the second experimental condition, subjects heard 12 105-dB tones, one-half of which were signal tones containing a brief gap in the middle. The subjects were required to respond to the tones containing the gap by pressing a foot pedal. No differences in tonic or phasic EDA were detected on the basis of unipolar or bipolar subtype, response to the dexamethasone suppression test, severity of depression, medication status, or sex. However, patients who exhibited features of psychomotor retardation had significantly lower levels of tonic EDA than did their nonretarded counterparts. The EDA of the depressed patients as a group was uniformly low. These results are consistent with other reports indicating that, with the exception of the retarded/nonretarded distinction, there are no differences in EDA among the various subtypes of depression.
为了确定能否根据皮肤电活动（EDA）对抑郁症患者亚组进行区分，记录了36名抑郁症患者在两种实验条件下的皮肤电导。在第一种条件下，受试者在收到旨在使其放松的指示后，听到10个85分贝的音调。在第二种实验条件下，受试者听到12个105分贝的音调，其中一半是中间有短暂间隙的信号音。受试者被要求通过踩脚踏板对包含间隙的音调做出反应。基于单极或双极亚型、对地塞米松抑制试验的反应、抑郁严重程度、用药情况或性别，未检测到静息或相位EDA的差异。然而，表现出精神运动迟缓特征的患者静息EDA水平明显低于无迟缓的患者。作为一个群体，抑郁症患者的EDA普遍较低。这些结果与其他报告一致，表明除了迟缓/非迟缓的区别外，抑郁症的各种亚型之间在EDA方面没有差异。
