血管活性肠肽对离体人逼尿肌条自发收缩活动的抑制作用
Inhibition of spontaneous contractile activity in isolated human detrusor muscle strips by vasoactive intestinal polypeptide.
作者信息
Kinder R B, Mundy A R
出版信息
Br J Urol. 1985 Feb;57(1):20-3. doi: 10.1111/j.1464-410x.1985.tb08976.x.
Abstract
In a study of 75 isolated human detrusor muscle strips, spontaneous contractions and an associated sustained rise in basal tension were observed in 43 (57%). Vasoactive intestinal polypeptide (VIP) caused significant reductions in the frequency and amplitude of spontaneous contractions and a fall in basal tension. The results suggest that VIP may have a role as an inhibitor of spontaneous activity in the human detrusor.
摘要
在一项对75条离体人逼尿肌条的研究中，在43条（57%）中观察到了自发收缩以及基础张力的相关持续升高。血管活性肠肽（VIP）可显著降低自发收缩的频率和幅度，并使基础张力下降。结果表明，VIP可能作为人逼尿肌自发活动的抑制剂发挥作用。
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