Allan W R, Kumar A
Br J Urol. 1985 Feb;57(1):46-9. doi: 10.1111/j.1464-410x.1985.tb08983.x.
In a randomised clinical trial of 100 consecutive patients treated by transurethral prostatectomy, half were given prophylactic intravenous mezlocillin. Blood cultures were obtained, the urine examined and the post-operative progress of each patient was carefully followed. The results were analysed and a high incidence of bacteraemia and septicaemia was found. Single-dose prophylactic mezlocillin was highly effective in preventing this complication. The presentation of septicaemia in mild and severe form is described and the aetiology discussed. Probable risk factors are identified and prophylactic and therapeutic measures described.
在一项对100例连续接受经尿道前列腺切除术治疗的患者进行的随机临床试验中，一半患者接受了预防性静脉注射美洛西林。采集血培养样本，检查尿液，并密切跟踪每位患者的术后进展。对结果进行分析后发现，菌血症和败血症的发生率很高。单剂量预防性使用美洛西林在预防这种并发症方面非常有效。描述了败血症的轻度和重度表现形式，并讨论了其病因。确定了可能的风险因素，并描述了预防和治疗措施。
