Sabatino Jolanda, Avesani Martina, Sirico Domenico, Reffo Elena, Castaldi Biagio, Bassareo PierPaolo, Di Salvo Giovanni
Department of Women's and Children's Health, University of Padua, Padua, Italy.
Paediatric Research Institute (IRP), Città Della Speranza, 35127, Padua, Italy.
Int J Cardiol Congenit Heart Dis. 2023 Apr 6;13:100456. doi: 10.1016/j.ijcchd.2023.100456. eCollection 2023 Sep.
Long-term effects of systemic hypertension (HTN) and HTN-mediated damages have been largely studied in non-congenital adult populations. By contrast, robust data about the predisposing factors, prevalence, consequences, and treatment of HTN in adults with congenital heart diseases (ACHD) is still scarce. Different mechanisms including the underlying cardiac disease, cardiac surgery and its consequences, the development of metabolic syndrome and secondary forms seem to play a role in HTN in ACHDs. To mitigate the potential long-term effects of HTN in this complex population, a meticulous follow-up is mandatory to identify patients who should receive treatment, and tailored strategies should be applied to obtain the best as possible result. Thus, this review will investigate risk factors, effects, and treatments of HTN in ACHD patients.
系统性高血压（HTN）及其介导的损害的长期影响在非先天性成年人群中已得到大量研究。相比之下，关于先天性心脏病（ACHD）成人患者中HTN的 predisposing 因素、患病率、后果及治疗的可靠数据仍然匮乏。包括潜在心脏病、心脏手术及其后果、代谢综合征的发展和继发性形式在内的不同机制似乎在ACHD患者的HTN中起作用。为减轻HTN对这一复杂人群的潜在长期影响，必须进行细致的随访以识别应接受治疗的患者，并应采用量身定制的策略以尽可能获得最佳结果。因此，本综述将研究ACHD患者中HTN的危险因素、影响及治疗方法。
