Lee Young Ho, Jun Jae-Bum
Department of Rheumatology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.
J Rheum Dis. 2025 Jan 1;32(1):3-7. doi: 10.4078/jrd.2024.0072. Epub 2024 Aug 14.
The management of rheumatoid arthritis (RA) follows a treat-to-target approach, as recommended by guidelines from the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR). RA treatment recommendations include an emphasis on frequent disease activity assessments to optimize therapy, recognizing the possibility of timely therapies to slow progression and improve long-term results. The evaluation of joint inflammation, pain, physical function, and clinical indicators is required for comprehensive RA therapy. Current therapeutic goals include achieving low disease activity or remission to enhance the quality of life (QoL) for patients. ACR-endorsed RA disease activity measures, such as the Disease Activity Score in 28 Joints with erythrocyte sedimentation rate or C-reactive protein level, Simplified Disease Activity Index (SDAI), Clinical Disease Activity Index (CDAI), Patient Activity Scale-II, and Routine Assessment of Patient Index Data 3, are recommended for their precision and sensitivity in supporting treat-to-target strategies. The ACR and EULAR have implemented Boolean-based and index-based remission criteria (SDAI and CDAI, respectively) to evaluate therapeutic effectiveness. The use of these markers regularly aligns with the ACR guidelines, improving adherence to quality indicators in clinical practice and confirming the provision of high-quality RA therapy. This review examines disease activity, function, and QoL measurements in line with the ACR and EULAR guidelines to aid doctors in treating Korean patients with RA.
类风湿关节炎（RA）的管理遵循美国风湿病学会（ACR）和欧洲抗风湿病联盟（EULAR）指南所推荐的达标治疗方法。RA治疗建议包括强调频繁进行疾病活动度评估以优化治疗，认识到及时治疗有可能减缓疾病进展并改善长期疗效。全面的RA治疗需要评估关节炎症、疼痛、身体功能和临床指标。当前的治疗目标包括实现低疾病活动度或缓解，以提高患者的生活质量（QoL）。推荐使用ACR认可的RA疾病活动度测量指标，如28个关节疾病活动评分（结合红细胞沉降率或C反应蛋白水平）、简化疾病活动指数（SDAI）、临床疾病活动指数（CDAI）、患者活动量表-II以及患者指数数据常规评估3，因为它们在支持达标治疗策略方面具有准确性和敏感性。ACR和EULAR分别采用基于布尔值和基于指数的缓解标准（分别为SDAI和CDAI）来评估治疗效果。定期使用这些指标符合ACR指南，可提高临床实践中对质量指标的依从性，并确保提供高质量的RA治疗。本综述根据ACR和EULAR指南审视疾病活动度、功能和QoL测量指标，以帮助医生治疗韩国RA患者。
