Owen Jacob J, Youssef Ronnie M, Altman Kirstin
Texas A&M School of Medicine, Dallas, TX, USA.
Department of Dermatology, Baylor Scott and White Medical Center - Temple, Temple, TX, USA.
Proc (Bayl Univ Med Cent). 2024 Sep 3;38(1):91-93. doi: 10.1080/08998280.2024.2392472. eCollection 2025.
Cutaneous acneiform eruptions are a side effect of many medications, including vitamin B12 therapy. However, reports of vitamin B12-induced acne are rare. We present a 67-year-old woman with a new diagnosis of pernicious anemia who developed a sudden acneiform eruption on the face after treatment with high-dose vitamin B12. Other medications that have been implicated in drug-induced acne include but are not limited to steroids, antibiotics, immunosuppressants, biologics, and vitamin B1 and B6. The pathogenesis is likely due to a transcriptome change in , the organism responsible for acne vulgaris. Cessation of the offending agent leads to a regression in symptoms.
皮肤痤疮样皮疹是许多药物的副作用，包括维生素B12治疗。然而，维生素B12诱发痤疮的报道很少。我们报告一名67岁新诊断为恶性贫血的女性，在接受高剂量维生素B12治疗后，面部突然出现痤疮样皮疹。其他与药物性痤疮有关的药物包括但不限于类固醇、抗生素、免疫抑制剂、生物制剂以及维生素B1和B6。其发病机制可能是由于寻常痤疮病原体的转录组变化。停用致病药物可使症状消退。
