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脊柱椎间盘炎的诊断与治疗:一项为期五年的单中心研究见解

Diagnosis and Treatment of Spondylodiscitis: Insights From a Five-Year Single-Center Study.

作者信息

Lima Diana, Lopes Nuno, Pereira Ana Lúcia, Rodrigues Diogo, Amaral-Silva Marta, Marques Elsa

机构信息

Physical Medicine and Rehabilitation, Hospital Curry Cabral, Unidade Local de Saúde de São José, Lisbon, PRT.

出版信息

Cureus. 2024 Nov 21;16(11):e74192. doi: 10.7759/cureus.74192. eCollection 2024 Nov.

DOI:10.7759/cureus.74192
PMID:39712729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11663236/
Abstract

INTRODUCTION

Spondylodiscitis is a rare but increasingly infectious disease affecting the intervertebral discs and vertebrae.

METHODS

This study retrospectively analyzed 36 patients admitted with spondylodiscitis over a five-year period, examining demographics, clinical features, risk factors, causative agents, treatment approaches, and outcomes.

RESULTS

The patient cohort had a mean age of 53.7 years, with a slight male predominance (55.6%, n=20). The most common symptoms were pain corresponding to 83.3% (n=30) followed by fever in 44.4% (n=16), and neurological symptoms were observed in 41.7% (n=15) of cases. The lumbar spine was the most frequently affected region (47.2%, n=17), and abscess formation, particularly involving the psoas muscle, occurred in 37.5% of cases. Notably, was the predominant causative agent representing 50% (n=18) of all cases. All patients received antibiotic treatment, and 47.2% (n=17) required additional surgical intervention. Rehabilitation was initiated during hospitalization for 86.1% (n=31) of patients with six patients transferred to a rehabilitation yard. The overall mortality rate was 11.1% (n=3), primarily due to septic shock.

CONCLUSION

This study underscores the challenges of diagnosing spondylodiscitis and highlights the importance of a multidisciplinary approach to management, involving early rehabilitation to improve functional outcomes.

摘要

引言

脊椎椎间盘炎是一种罕见但感染性日益增加的疾病,影响椎间盘和椎体。

方法

本研究回顾性分析了五年期间收治的36例脊椎椎间盘炎患者,检查了人口统计学、临床特征、危险因素、病原体、治疗方法和结果。

结果

患者队列的平均年龄为53.7岁,男性略占优势(55.6%,n = 20)。最常见的症状是疼痛,占83.3%(n = 30),其次是发热,占44.4%(n = 16),41.7%(n = 15)的病例出现神经症状。腰椎是最常受累的部位(47.2%,n = 17),37.5%的病例出现脓肿形成,尤其是累及腰大肌。值得注意的是, 是主要病原体,占所有病例的50%(n = 18)。所有患者均接受了抗生素治疗,47.2%(n = 17)的患者需要额外的手术干预。86.1%(n = 31)的患者在住院期间开始康复治疗,6名患者被转到康复病房。总死亡率为11.1%(n = 3),主要原因是感染性休克。

结论

本研究强调了诊断脊椎椎间盘炎的挑战,并突出了多学科管理方法的重要性,包括早期康复以改善功能结果。

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Spondylodiscitis in adults: diagnosis and management.成人脊椎炎:诊断与治疗。
Br J Hosp Med (Lond). 2022 Oct 2;83(10):1-9. doi: 10.12968/hmed.2021.0448. Epub 2022 Oct 30.
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A systematic review: characteristics, complications and treatment of spondylodiscitis.系统回顾:椎间盘炎的特征、并发症及治疗。
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