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一名长期使用氯胺酮患者的多器官功能衰竭：病例报告

Multi-organ Failure in a Patient With Chronic Ketamine Use: A Case Report.

作者信息

Okunlola Ayoyimika O, Sufrian Syahmina, Ajao Temitope O, Uzzaman G K M Rashik, Fernandez Cornelius J

机构信息

Internal Medicine, United Lincolnshire Hospitals NHS Trust, Lincolnshire, GBR.

General and Acute Medicine, United Lincolnshire Hospitals NHS Trust, Lincolnshire, GBR.

出版信息

Cureus. 2024 Nov 21;16(11):e74158. doi: 10.7759/cureus.74158. eCollection 2024 Nov.

DOI:10.7759/cureus.74158
PMID:39712781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11662961/
Abstract

Ketamine is increasingly used as a recreational drug. The report outlines the various multi-organ dysfunctions identified following chronic abuse in a 24-year-old patient with no significant past medical history and the subsequent patient management. Besides ketamine cessation, other treatments only provide suboptimal relief to the damage inflicted by the toxic ketamine metabolites.

摘要

氯胺酮越来越多地被用作消遣性毒品。本报告概述了一名24岁无重大既往病史的患者在长期滥用氯胺酮后出现的各种多器官功能障碍以及后续的患者管理情况。除了停用氯胺酮外，其他治疗方法对有毒氯胺酮代谢产物造成的损害只能提供不太理想的缓解。

相似文献

1
Multi-organ Failure in a Patient With Chronic Ketamine Use: A Case Report.一名长期使用氯胺酮患者的多器官功能衰竭：病例报告
Cureus. 2024 Nov 21;16(11):e74158. doi: 10.7759/cureus.74158. eCollection 2024 Nov.
2
Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.慢性氯胺酮滥用相关的胆汁淤积和胆管扩张：病例系列研究。
Singapore Med J. 2011 Mar;52(3):e52-5.
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Sphincter of oddi dysfunction induced by ketamine: A case report.氯胺酮诱发的Oddi括约肌功能障碍：一例报告。
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Severe Ketamine-Induced Uropathy Associated With Cholangiopathy Requiring Percutaneous Nephrostomy.严重氯胺酮诱发的尿路病伴胆管病，需行经皮肾造瘘术
Cureus. 2022 Oct 18;14(10):e30443. doi: 10.7759/cureus.30443. eCollection 2022 Oct.
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Cureus. 2024 Oct 4;16(10):e70804. doi: 10.7759/cureus.70804. eCollection 2024 Oct.
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Multiorgan dysfunction related to chronic ketamine abuse.与慢性氯胺酮滥用相关的多器官功能障碍。
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Severe Encephalatrophy and Related Disorders From Long-Term Ketamine Abuse: A Case Report and Literature Review.长期滥用氯胺酮所致严重脑萎缩及相关疾病：一例报告及文献综述
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Newer therapies and surgical management of ketamine-induced uropathy: A review.新型疗法和手术治疗氯胺酮相关性尿路病变：综述。
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本文引用的文献

1
Ketamine Induced Acute Systolic Heart Failure.氯胺酮诱发的急性收缩性心力衰竭。
Eur J Case Rep Intern Med. 2024 Apr 23;11(6):004470. doi: 10.12890/2024_004470. eCollection 2024.
2
Ketamine restriction correlates with reduced cholestatic liver injury and improved outcomes in critically ill patients with burn injury.氯胺酮限制与烧伤重症患者胆汁淤积性肝损伤减轻及预后改善相关。
JHEP Rep. 2023 Nov 2;6(2):100950. doi: 10.1016/j.jhepr.2023.100950. eCollection 2024 Feb.
3
Ketamine-Induced Acute Interstitial Nephritis.氯胺酮诱发的急性间质性肾炎。
Kidney Int Rep. 2022 Dec 30;8(4):929-931. doi: 10.1016/j.ekir.2022.12.015. eCollection 2023 Apr.
4
Current approaches for the treatment of ketamine-induced cystitis.氯胺酮诱发膀胱炎的当前治疗方法。
Neurourol Urodyn. 2023 Mar;42(3):680-689. doi: 10.1002/nau.25148. Epub 2023 Feb 13.
5
Brain Changes Associated With Long-Term Ketamine Abuse, A Systematic Review.长期滥用氯胺酮相关的脑变化：一项系统综述
Front Neuroanat. 2022 Mar 18;16:795231. doi: 10.3389/fnana.2022.795231. eCollection 2022.
6
Oral ketamine induced pathological changes of the urinary tract in a rat model.口服氯胺酮在大鼠模型中诱发尿路病理变化。
Malays J Pathol. 2017 Apr;39(1):47-53.
7
Cholestasis and biliary dilatation associated with chronic ketamine abuse: a case series.慢性氯胺酮滥用相关的胆汁淤积和胆管扩张：病例系列研究。
Singapore Med J. 2011 Mar;52(3):e52-5.
8
Taming the ketamine tiger. 1965.驯服氯胺酮这只老虎。1965 年。
Anesthesiology. 2010 Sep;113(3):678-84. doi: 10.1097/ALN.0b013e3181ed09a2.
9
Mice are prone to kidney pathology after prolonged ketamine addiction.长期氯胺酮成瘾后，小鼠易出现肾脏病变。
Toxicol Lett. 2009 Dec 15;191(2-3):275-8. doi: 10.1016/j.toxlet.2009.09.006. Epub 2009 Sep 17.
10
Ketamine-associated bladder dysfunction.氯胺酮相关性膀胱功能障碍
Int J Urol. 2009 Oct;16(10):826-9. doi: 10.1111/j.1442-2042.2009.02361.x. Epub 2009 Jul 29.