Regal A M, Reese P, Antkowiak J, Hart T, Takita H
Cancer. 1985 Mar 15;55(6):1334-9. doi: 10.1002/1097-0142(19850315)55:6<1334::aid-cncr2820550629>3.0.co;2-t.
Aggressive management of malignant primary tumors and their metastatic manifestations is associated with improved survival outcomes. As investigators continue to focus attention on the ablation or control of pulmonary metastatic foci, surgery is gaining importance in the treatment of metastatic disease to the lungs and, in this context, is adjunctive to other therapeutic modalities. At Roswell Park Memorial Institute (RPMI), median sternotomy is preferred to unilateral or staged bilateral thoracotomies, since the former provides simultaneous access to both hemithoraces, whereas its lower morbidity facilitates the earlier resumption of systemic therapy. The RPMI experience, amassed from 131 patients and using this procedure, is presented and analyzed with respect to patient survival.
对恶性原发性肿瘤及其转移表现进行积极治疗与生存结果改善相关。随着研究人员继续将注意力集中在肺转移灶的消融或控制上,手术在治疗肺部转移性疾病中的重要性日益凸显,在此背景下,手术是其他治疗方式的辅助手段。在罗斯韦尔公园纪念研究所(RPMI),正中胸骨切开术比单侧或分期双侧开胸术更受青睐,因为前者可同时进入双侧胸腔,而且其较低的发病率有助于更早恢复全身治疗。本文介绍并分析了RPMI对131例患者采用该手术方法后的生存情况。