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模拟恶性外周神经鞘瘤的腭部细胞性施万瘤:一场诊断马拉松。

Cellular Schwannoma of the Palate Simulating as Malignant Peripheral Nerve Sheath Tumor: A Diagnostic Marathon.

作者信息

Bajpai Manas, Mani Amit, L Sabnis Saurabh, Rani Rm Vatchala

机构信息

Dept. of Oral and Maxillofacial Pathology and Oral Microbiology, Rural Dental College Pravara Institute of Medical Sciences, Loni (Maharashtra), India.

Dept. of Periodontology, Rural Dental College, Pravara Institute of Medical Sciences, Loni (Maharashtra) India.

出版信息

J Dent (Shiraz). 2024 Dec 1;25(4):383-387. doi: 10.30476/dentjods.2024.101035.2265. eCollection 2024 Dec.

Abstract

Schwannomas are considered benign soft tissue tumors that originate from Schwann cells. Oral Schwannomas are rare and account for only 1% of all Schwannomas. Cellularschwannoma (CS) is a rare histological variant of schwannoma, characterized by high cellularity and cellular atypia. We present a case of localized growth of palatal mucosa that imitated the features of malignant peripheral nerve sheath tumor (MPNST) on histopathological examination; it was differentiated from MPNST by the correlation of clinical, histopathological, and immunohistochemical features.

摘要

神经鞘瘤被认为是起源于施万细胞的良性软组织肿瘤。口腔神经鞘瘤较为罕见,仅占所有神经鞘瘤的1%。细胞性神经鞘瘤(CS)是神经鞘瘤一种罕见的组织学变异型,其特征为细胞密度高和细胞异型性。我们报告一例腭黏膜局限性生长病例,该病例在组织病理学检查中表现出恶性外周神经鞘膜瘤(MPNST)的特征;通过临床、组织病理学和免疫组化特征的相关性,将其与MPNST区分开来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6c4/11662178/bdecbda0bfee/JDS-25-383-g001.jpg

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