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刚果共和国麻疹疫苗接种者中低IgG血清转化情况

Low IgG Seroconversion among Persons Vaccinated against Measles, Republic of Congo.

作者信息

Mavoungou Yanne Vanessa Thiécesse, Gangoué Léa Gwladys, Koukouikila-Koussounda Félix, Nkoua Cynthia Badzi, Mayengue Pembe Issamou, Kankou Jean-Medard, Kiminou Pathou Christelle, Mahoukou Princesse, Dossou-Yovo Louis Régis, Ahombo Gabriel, Niama Fabien Roch

出版信息

Emerg Infect Dis. 2025 Jan;31(1):197-199. doi: 10.3201/eid3101.240911.

DOI:10.3201/eid3101.240911
PMID:39714480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11682821/
Abstract

We report a low (38.7%; p<0.0001) level of IgG seroconversion in patients who were positive for measles virus IgM in the Republic of Congo, despite a history of vaccination. Considering this country's recurring measles epidemics, more effective immunization strategies, including vaccine delivery methods, are needed to prevent measles outbreaks.

摘要

我们报告称,在刚果共和国,尽管有疫苗接种史,但麻疹病毒IgM呈阳性的患者中,IgG血清转化率较低(38.7%;p<0.0001)。鉴于该国麻疹疫情反复出现,需要更有效的免疫策略,包括疫苗接种方式,以预防麻疹暴发。

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引用本文的文献

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Long-term measles antibody profiles following different vaccine schedules in China, a longitudinal study.中国不同疫苗接种方案后麻疹抗体的长期变化特征:一项纵向研究。
Nat Commun. 2023 Mar 29;14(1):1746. doi: 10.1038/s41467-023-37407-x.
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Assessing measles vaccine failure in Tianjin, China.评估中国天津麻疹疫苗失败的情况。
Vaccine. 2019 May 31;37(25):3251-3254. doi: 10.1016/j.vaccine.2019.05.005. Epub 2019 May 8.
3
Letter to the editor: Measles cases among fully vaccinated persons.致编辑的信:完全接种疫苗人群中的麻疹病例
Euro Surveill. 2018 Aug;23(34). doi: 10.2807/1560-7917.ES.2018.23.34.1800449.
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Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique.白细胞介素-4/白细胞介素-13通路中的基因变异影响莫桑比克儿童的麻疹疫苗反应和疫苗接种失败情况。
Viral Immunol. 2017 Sep;30(7):472-478. doi: 10.1089/vim.2017.0014. Epub 2017 Jun 8.
5
Field evaluation of measles vaccine effectiveness among children in the Democratic Republic of Congo.刚果民主共和国儿童麻疹疫苗有效性的现场评估
Vaccine. 2015 Jun 26;33(29):3407-14. doi: 10.1016/j.vaccine.2015.04.067. Epub 2015 Apr 30.