体重指数与前列腺体积的相关性：前列腺癌患者术前和术后测量值的回顾性分析

The Correlation Between Body Mass Index and Prostate Volume: A Retrospective Analysis of Pre and Postoperative Measurements in Prostate Cancer Patients.

作者信息

Barone Biagio, Amicuzi Ugo, Massanova Matteo, Napolitano Luigi, Reccia Pasquale, Mirto Benito Fabio, Balsamo Raffaele, Giudice Francesco Del, Ferro Matteo, Busetto Gian Maria, Tataru Octavian Sabin, Lucarelli Giuseppe, Manfredi Celeste, Biondo Dario Del, Caputo Vincenzo Francesco, Falabella Roberto, Fusco Ferdinando, Imbimbo Ciro, Crocetto Felice

机构信息

Department of Urology, Ospedale San Paolo, Naples, Italy.

Department of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.

出版信息

Prostate. 2025 Apr;85(5):433-442. doi: 10.1002/pros.24845. Epub 2024 Dec 23.

BACKGROUND

This study aims to assess the relationship between body mass index (BMI) and prostate volume, utilizing pre and postoperative measurements.

METHODS

A retrospective, observational study was conducted at a single site using data from an institutional database. Medical records of patients who underwent robot-assisted radical prostatectomy were reviewed. Data included age, BMI, and prostate volumes measured through digital rectal exam (DRE), transrectal ultrasound (TRUS), magnetic resonance imaging (MRI), and surgical specimen weight (SPW).

RESULTS

A total of 168 patients were identified and included in the analysis. Spearman's correlation test revealed a significant association between BMI and prostate volume for all measurement methods, reporting r = 0.146 (p = 0.047) for DRE, r = 0.268 (p < 0.0001) for TRUS, r = 0.177 (p = 0.021) for MRI and r = 0.234 (p = 0.002) for SPW. Linear regression analysis confirmed the significant association between BMI and prostate volume, reporting, respectively, R = 0.026 (p = 0.036) for DRE, R = 0.076 (p < 0.0001) for TRUS, R = 0.038 (p = 0.011) for MRI and R = 0.040 (p = 0.009) for SPW. Notably, considering the SPW the best way to estimate prostate volume, for every increase in BMI, the predicted increase of prostate volume is 0.865gr.

CONCLUSIONS

This study demonstrates a positive linear correlation between BMI and prostate volume, highlighting the importance of considering BMI in prostate volume assessments.

背景

本研究旨在利用术前和术后测量数据评估体重指数（BMI）与前列腺体积之间的关系。

方法

在单一研究点进行了一项回顾性观察研究，使用机构数据库中的数据。对接受机器人辅助根治性前列腺切除术的患者的病历进行了回顾。数据包括年龄、BMI以及通过直肠指检（DRE）、经直肠超声（TRUS）、磁共振成像（MRI）测量的前列腺体积和手术标本重量（SPW）。

结果

共识别出168例患者并纳入分析。Spearman相关性检验显示，对于所有测量方法，BMI与前列腺体积之间均存在显著关联，DRE的r = 0.146（p = 0.047），TRUS的r = 0.268（p < 0.0001），MRI的r = 0.177（p = 0.021），SPW的r = 0.234（p = 0.002）。线性回归分析证实了BMI与前列腺体积之间的显著关联，DRE的R = 0.026（p = 0.036），TRUS的R = 0.076（p < 0.0001），MRI的R = 0.038（p = 0.011），SPW的R = 0.040（p = 0.009）。值得注意的是，考虑到SPW是估计前列腺体积的最佳方法，BMI每增加一个单位，前列腺体积的预测增加量为0.865克。