Liang Xinshuo, Meng Shuo, Zhi Chuanwei, Zhang Shuai, Tan Renjie, Xu Xingyuan, Huang Kaisong, Lei Leqi, Hu Jinlian
Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, 999077, China.
Adv Healthc Mater. 2025 Mar;14(6):e2403780. doi: 10.1002/adhm.202403780. Epub 2024 Dec 23.
The advent of bionic skin sensors represents a significant leap forward in the realm of wearable health monitoring technologies. Existing bionic skin technologies face several limitations, including complex and expensive manufacturing processes, low wearing comfort, and challenges in achieving comfortable real-time health monitoring. These shortcomings hinder the widespread adoption and practical utility of bionic skin in various applications. The bionic skin invention presented in this article addresses these issues by introducing a novel thermal transfer manufacturing process that is low-cost and easy to operate. This method is particularly suitable for the small-scale mass production required for bionic skin applications. Additionally, the innovative bilayer unidirectional moisture transport nanomembrane incorporated into the bionic skin offers high extensibility and breathability. This feature enhances the ability of the skin to absorb sweat, thereby facilitating comfortable real-time health monitoring. The specially designed bionic skin sensor embedded within this system can monitor various biomarkers in sweat, including glucose, lactic acid, uric acid, pH, temperature, and skin impedance. When combined with the CARE(Continuous Analyte Monitoring with Real-time Engagement) system, it enables real-time data transmission and processing, offering a comprehensive approach to health monitoring that is both comfortable and reliable.
仿生皮肤传感器的出现代表了可穿戴健康监测技术领域的重大飞跃。现有的仿生皮肤技术面临着几个局限性，包括复杂且昂贵的制造工艺、佩戴舒适度低，以及在实现舒适的实时健康监测方面存在挑战。这些缺点阻碍了仿生皮肤在各种应用中的广泛采用和实际效用。本文介绍的仿生皮肤发明通过引入一种低成本且易于操作的新型热转印制造工艺来解决这些问题。这种方法特别适合仿生皮肤应用所需的小规模批量生产。此外，集成到仿生皮肤中的创新型双层单向水分传输纳米膜具有高延展性和透气性。这一特性增强了皮肤吸收汗液的能力，从而便于进行舒适的实时健康监测。嵌入该系统的特殊设计的仿生皮肤传感器可以监测汗液中的各种生物标志物，包括葡萄糖、乳酸、尿酸、pH值、温度和皮肤阻抗。当与CARE（实时参与连续分析物监测）系统结合使用时，它能够实现实时数据传输和处理，提供一种既舒适又可靠的全面健康监测方法。
