Department of Biomedical Engineering, City University of Hong Kong, Hong Kong SAR, 999077, China.
School of Fashion and Textiles, The Hong Kong Polytechnic University, 999077, Hong Kong SAR, China.
Adv Mater. 2024 Apr;36(17):e2306435. doi: 10.1002/adma.202306435. Epub 2023 Sep 20.
Developing an intelligent wearable system is of great significance to human health management. An ideal health-monitoring patch should possess key characteristics such as high air permeability, moisture-wicking function, high sensitivity, and a comfortable user experience. However, such a patch that encompasses all these functions is rarely reported. Herein, an intelligent bionic skin patch for health management is developed by integrating bionic structures, nano-welding technology, flexible circuit design, multifunctional sensing functions, and big data analysis using advanced electrospinning technology. By controlling the preparation of nanofibers and constructing bionic secondary structures, the resulting nanofiber membrane closely resembles human skin, exhibiting excellent air/moisture permeability, and one-side sweat-wicking properties. Additionally, the bionic patch is endowed with a high-precision signal acquisition capabilities for sweat metabolites, including glucose, lactic acid, and pH; skin temperature, skin impedance, and electromyographic signals can be precisely measured through the in situ sensing electrodes and flexible circuit design. The achieved intelligent bionic skin patch holds great potential for applications in health management systems and rehabilitation engineering management. The design of the smart bionic patch not only provides high practical value for health management but also has great theoretical value for the development of the new generation of wearable electronic devices.
开发智能可穿戴系统对人类健康管理具有重要意义。理想的健康监测贴片应具备高透气性、吸湿功能、高灵敏度和舒适的用户体验等关键特性。然而，很少有报道涵盖所有这些功能的贴片。在此，通过先进的静电纺丝技术，整合仿生结构、纳米焊接技术、柔性电路设计、多功能传感功能和大数据分析，开发了一种用于健康管理的智能仿生皮肤贴片。通过控制纳米纤维的制备和构建仿生二级结构，得到的纳米纤维膜与人体皮肤非常相似，具有优异的空气/湿气透过性和单面排汗性能。此外，仿生贴片具有高精度的汗液代谢物（如葡萄糖、乳酸和 pH 值）信号采集能力；通过原位传感电极和柔性电路设计，可以精确测量皮肤温度、皮肤阻抗和肌电信号。所实现的智能仿生皮肤贴片在健康管理系统和康复工程管理中具有广阔的应用前景。智能仿生贴片的设计不仅为健康管理提供了很高的实用价值，而且对新一代可穿戴电子设备的发展具有重要的理论价值。
