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肯尼亚贫民窟成年居民中与代谢综合征改善相关的社会人口学因素:一项随机对照试验

Sociodemographic Factors Associated with Improved Metabolic Syndrome in Slum Dwelling Adults in Kenya: A Randomized Controlled Trial.

作者信息

Okube Okubatsion Tekeste, Kimani Samuel T

机构信息

School of Nursing, The Catholic University of Eastern Africa, Nairobi, Kenya.

School of Nursing Sciences, University of Nairobi, Nairobi, Kenya.

出版信息

SAGE Open Nurs. 2024 Dec 22;10:23779608241299647. doi: 10.1177/23779608241299647. eCollection 2024 Jan-Dec.

Abstract

BACKGROUND

Sociodemographic factors have been implicated in cardiovascular health with differential morbidity and mortality. It is essential to comprehend how sociodemographic factors contribute to the improvement of Metabolic Syndrome (MetS), the primary cardiovascular diseases indicator.

OBJECTIVE

Determine the role of sociodemographic factors in improving MetS among adults residing in the Slums of Nairobi, Kenya.

METHODS

Adults with MetS participated in this randomized controlled trial study for a period of 12-months. A random assignment was used to place eligible participants in the intervention or control groups. The intervention group received lifestyle intervention that entails not using tobacco products or alcohol, exercising, and adhering to recommended dietary guidelines, while the control group had standard medical care. Clinical, biochemistry, and lifestyle habits were measured before and a year after the intervention. The association between the sociodemographic factors and the improvement in MetS was examined using a multiple logistic regression model .

RESULTS

In the intervention group, lack of improvement in metabolic syndrome was significantly higher among aged (≥50 years) respondents [AOR = 9.097;  < .001]; Protestants [AOR = 7.292;  = .017] and Catholics [AOR = 5.270;  = .050]. Compared to unemployed, formally employed respondents had an 84.6% lower chance of having MetS [AOR = 0.154;  = .005]. Within the control group, lack of improvement in metabolic syndrome was significantly higher among aged (≥50 years) respondents [AOR = 5.013;  = .047]. Compared to respondents who had less than $100, individuals with monthly incomes between $100 and $500 had a roughly 10-fold [AOR = 10.499;  = .024] higher chance of having MetS.

CONCLUSION

In the current study, the findings show that sociodemographic factors namely: advanced age, unemployment, being Protestants and Catholics as well as higher income were negatively associated with improvement in MetS. The findings indicate that social factors have impact in the management and intervention outcomes of CVDs. Programmers and policy makers should plan interventions for CVD prevention and response with these factors in mind.

摘要

背景

社会人口学因素与心血管健康相关,其发病率和死亡率存在差异。理解社会人口学因素如何促进代谢综合征(MetS)的改善至关重要,代谢综合征是主要的心血管疾病指标。

目的

确定社会人口学因素在改善肯尼亚内罗毕贫民窟成年人代谢综合征方面的作用。

方法

患有代谢综合征的成年人参与了这项为期12个月的随机对照试验研究。采用随机分配将符合条件的参与者分为干预组或对照组。干预组接受生活方式干预,包括不使用烟草制品或酒精、锻炼以及遵循推荐的饮食指南,而对照组接受标准医疗护理。在干预前和干预一年后测量临床、生化指标和生活习惯。使用多元逻辑回归模型检验社会人口学因素与代谢综合征改善之间的关联。

结果

在干预组中,年龄较大(≥50岁)的受访者代谢综合征改善不足的情况显著更高 [调整后比值比(AOR)= 9.097;P <.001];新教徒 [AOR = 7.292;P = 0.017] 和天主教徒 [AOR = 5.270;P = 0.050]。与失业者相比,正式就业的受访者患代谢综合征的可能性低84.6% [AOR = 0.154;P = 0.005]。在对照组中,年龄较大(≥50岁)的受访者代谢综合征改善不足的情况显著更高 [AOR = 5.013;P = 0.047]。与月收入低于100美元的受访者相比,月收入在100美元至500美元之间的个体患代谢综合征的可能性大约高10倍 [AOR = 10.499;P = 0.024]。

结论

在当前研究中,结果表明社会人口学因素,即:高龄、失业、新教徒和天主教徒身份以及较高收入与代谢综合征的改善呈负相关。研究结果表明社会因素对心血管疾病的管理和干预结果有影响。规划者和政策制定者在规划心血管疾病预防和应对干预措施时应考虑这些因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9535/11664520/655d8fb7ec33/10.1177_23779608241299647-fig1.jpg

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