Khan Saeed A, Brenner Thomas, Link Ann-Christine, Reudenbach Christoph, Bendix Jörg, Weckler Barbara C, Kutzinski Max, Rupp Jan, Witzenrath Martin, Rohde Gernot, Pletz Mathias W, Bertrams Wilhelm, Schmeck Bernd
Department of Geography, Philipps-Universität Marburg, Marburg, Germany.
Institute for Lung Research, German Center for Lung Research (DZL), Universities of Giessen and Marburg Lung Centre, Philipps-Universität Marburg, Marburg, Germany.
Int J Biometeorol. 2025 Mar;69(3):695-702. doi: 10.1007/s00484-024-02839-7. Epub 2024 Dec 24.
Community-acquired pneumonia (CAP) is a major global health concern as it is a leading cause of morbidity, mortality and economic burden to the health care systems. In Germany, more than 15,000 people die every year from CAP. Climate change is altering weather patterns, and it may influence the probability and severity of CAP. The increasing frequency and intensity of extreme weather events necessitate the study of their impact on CAP hospitalizations. In this regard, we examine the influence of absolute values and changes in various meteorological and air quality conditions on the frequency of CAP hospitalizations. We matched weather data to the German CAPNETZ-Cohort of 10,660 CAP patients from 22 healthcare facilities between 2003 and 2017. Our findings show that daily fluctuations in meteorological conditions (maximum temperature, 99th percentile precipitation), apart from relative humidity, are likely to result in triggering CAP hospitalizations than absolute conditions. In contrast, the absolute values of air quality (CO, NO, O, PM, SO, and total aerosols) are found to exert a greater influence on CAP hospitalizations than changes in air quality. The study outcomes have implications for public health measures, early warning systems, and public awareness, with the aim of mitigating the risk of CAP.
社区获得性肺炎（CAP）是一个重大的全球健康问题，因为它是发病、死亡以及医疗保健系统经济负担的主要原因。在德国，每年有超过15000人死于社区获得性肺炎。气候变化正在改变天气模式，可能会影响社区获得性肺炎的发病几率和严重程度。极端天气事件的频率和强度不断增加，这就需要研究它们对社区获得性肺炎住院情况的影响。在这方面，我们研究了各种气象和空气质量条件的绝对值及变化对社区获得性肺炎住院频率的影响。我们将2003年至2017年期间来自22个医疗机构的10660名社区获得性肺炎患者的德国CAPNETZ队列与气象数据进行了匹配。我们的研究结果表明，除相对湿度外，气象条件（最高温度、第99百分位降水量）的每日波动比绝对值更有可能导致社区获得性肺炎住院。相比之下，发现空气质量（一氧化碳、一氧化氮、臭氧、颗粒物、二氧化硫和总气溶胶）的绝对值对社区获得性肺炎住院的影响大于空气质量的变化。研究结果对公共卫生措施、早期预警系统和公众意识具有启示意义，目的是降低社区获得性肺炎的风险。
