多西环素暴露后预防适用人群中的金黄色葡萄球菌四环素耐药性及共耐药性
Staphylococcus aureus Tetracycline Resistance and Co-resistance in a Doxycycline Postexposure Prophylaxis-Eligible Population.
作者信息
Mittelstaedt Rachel, Kanjilal Sanjat, Helekal David, Robbins Gregory K, Grad Yonatan H
机构信息
Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital.
Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health.
出版信息
J Infect Dis. 2025 Apr 15;231(4):e708-e712. doi: 10.1093/infdis/jiae634.
Among doxycycline postexposure prophylaxis (doxy-PEP)-eligible men, Staphylococcus aureus tetracycline nonsusceptibility is more prevalent than in the overall population and is associated with resistance to trimethoprim-sulfamethoxazole and clindamycin. Doxy-PEP may select for multidrug-resistant S aureus, underscoring the importance of surveillance.
在符合强力霉素暴露后预防（强力霉素-PEP）条件的男性中，金黄色葡萄球菌对四环素不敏感的情况比总体人群中更普遍，并且与对甲氧苄啶-磺胺甲恶唑和克林霉素的耐药性相关。强力霉素-PEP可能会选择出耐多药金黄色葡萄球菌，这突出了监测的重要性。
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