Çimen Duygu, Ünal Serhat, Denizli Adil
Department of Chemistry, Hacettepe University, Ankara, Turkey.
Department of Infectious Disease and Clinical Microbiology, Hacettepe University, Ankara, Turkey.
Anal Biochem. 2025 Mar;698:115753. doi: 10.1016/j.ab.2024.115753. Epub 2024 Dec 22.
Nanotechnology is an important science that finds a wide range of applications from energy production to industrial production processes and biomedical applications. Nanoparti-cles, which are the most frequently preferred nanomaterials that form the basis of nanotechnolo-gy, are prepared with different composition, size, shape and surface chemistry to provide new techniques in applications in many different fields. The use of nanoparticles in the preparation of plasmonic sensors has increased the interest in plasmonic sensors such as surface plasmon resonance, electrochemical sensors, surface enhanced raman scattering and colorimetric sensors due to their increased sensing capacity on sensor surfaces. Plasmonic sensors are an important option in many different fields, such as medicine, environmental agriculture and food safety, thanks to their ability to solve a multitude of challenges. Because, plasmonic sensors are defined as sensing devices with important features such as sensitive and fast detection, no need for labels, real-time analysis, portability. In this review, the information about nanoparticles and their types and working principles of plasmonic sensors is given. Then, examples in clinical applications using different plasmonic sensors prepared with plasmonic nanoparticles are discussed in detail.
纳米技术是一门重要的科学，其应用范围广泛，涵盖从能源生产到工业生产过程以及生物医学应用等诸多领域。纳米粒子是构成纳米技术基础的最常被选用的纳米材料，人们通过不同的组成、尺寸、形状和表面化学性质来制备纳米粒子，以便在许多不同领域的应用中提供新技术。由于纳米粒子在传感器表面的传感能力增强，其在等离子体传感器制备中的应用增加了人们对表面等离子体共振、电化学传感器、表面增强拉曼散射和比色传感器等等离子体传感器的兴趣。等离子体传感器凭借其解决众多挑战的能力，在医学、环境农业和食品安全等许多不同领域都是一个重要选择。因为，等离子体传感器被定义为具有灵敏快速检测、无需标记、实时分析、便携等重要特性的传感设备。在这篇综述中，给出了有关纳米粒子及其类型以及等离子体传感器工作原理的信息。然后，详细讨论了使用由等离子体纳米粒子制备的不同等离子体传感器在临床应用中的实例。
