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一种罕见的变异型,沃辛样乳头状甲状腺癌:一例报告。

An uncommon variant, Warthin‑like papillary thyroid carcinoma: A case report.

作者信息

Altunsu Sena, Dagdemir Baris, Toper Muhammed Hasan, Ari Nursah, Ergenc Muhammer

机构信息

Department of General Surgery, Marmara University School of Medicine, 34854 Istanbul, Turkey.

Department of Pathology, Marmara University School of Medicine, 34854 Istanbul, Turkey.

出版信息

Mol Clin Oncol. 2024 Dec 10;22(2):16. doi: 10.3892/mco.2024.2811. eCollection 2025 Feb.

Abstract

The most prevalent form of thyroid cancer is papillary thyroid carcinoma, of which warthin-like papillary thyroid carcinoma (WLPTC) is an uncommon variant. The symptoms, diagnosis and course of treatment for this subtype of papillary thyroid cancer are comparable to those of the classic variety. It is usually associated with Hashimoto's thyroiditis and is considered to have a favourable prognosis. In the present case report, a 40-year-old female patient was presented with multiple thyroid nodules and subclinical hypothyroidism. The female patient underwent a total thyroidectomy after a fine needle aspiration biopsy revealed an atypia of undetermined significance in one of the nodules, along with a family history of thyroid cancer. The definitive pathological assessment revealed seven thyroid nodules with four different diagnoses, one of which was WLPTC.

摘要

甲状腺癌最常见的类型是乳头状甲状腺癌,其中沃辛样乳头状甲状腺癌(WLPTC)是一种罕见的变体。这种乳头状甲状腺癌亚型的症状、诊断和治疗过程与经典类型相似。它通常与桥本甲状腺炎相关,并且被认为预后良好。在本病例报告中,一名40岁女性患者出现多个甲状腺结节和亚临床甲状腺功能减退。在细针穿刺活检显示其中一个结节存在意义未明的异型性且有甲状腺癌家族史后,该女性患者接受了甲状腺全切术。最终病理评估显示有七个甲状腺结节,有四种不同诊断,其中之一是WLPTC。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f31d/11667444/8b14d18e9575/mco-22-02-02811-g00.jpg

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