Kumar Tarun, Nigam Jitendra S, Tewari Prerna, Jha Chandan K
Pathology, All India Institute of Medical Sciences, Patna, IND.
Pathology/Lab Medicine, All India Institute of Medical Sciences, Patna, IND.
Cureus. 2020 Dec 28;12(12):e12350. doi: 10.7759/cureus.12350.
Papillary thyroid carcinoma (PTC) is one of the most common thyroid malignancy with various histologic variants. Acknowledging the correct histological variant of PTC helps to know about the tumor's nature and prognosis. The Warthin-like variant of papillary thyroid (WLPTC), a newly described histologic variant of PTC, is relatively uncommon. A 16-year-old female presented with complaints of painful thyroid swelling for two years. Fine needle aspiration cytology (FNAC) from the lobes showed lymphocytic thyroiditis features with Hurthle cell change. Sections from the left lobe revealed a diagnosis of a Warthin‑like variant of PTC without nodal metastasis. WLPTC is a rare variant having a favorable outcome due to the absence of lymph node metastasis, extra-thyroidal extension, and a low recurrence rate. The correct cytological and histomorphological features are of utmost importance to render the diagnosis of WLPTC for better management.
乳头状甲状腺癌（PTC）是最常见的甲状腺恶性肿瘤之一，具有多种组织学变异型。明确PTC正确的组织学变异型有助于了解肿瘤的性质和预后。甲状腺乳头状癌的沃辛样变异型（WLPTC）是一种新描述的PTC组织学变异型，相对少见。一名16岁女性因甲状腺疼痛性肿大两年前来就诊。对甲状腺叶进行细针穿刺细胞学检查（FNAC）显示为淋巴细胞性甲状腺炎特征伴许特耳细胞改变。左叶切片显示诊断为无淋巴结转移的PTC沃辛样变异型。WLPTC是一种罕见的变异型，由于无淋巴结转移、甲状腺外侵犯且复发率低，预后良好。正确的细胞学和组织形态学特征对于诊断WLPTC以实现更好的治疗管理至关重要。
