甲状腺乳头状癌的沃辛样变异型——罕见肿瘤病例报告并文献复习
Warthin-like variant of Papillary thyroid carcinoma-Case report of an uncommon tumour with review of literature.
作者信息
Sahoo Pradyumna Kumar, Patnayak Rashmi, Khan Perwez Alam, Jena Amitabh
机构信息
Department of Surgical Oncology, Institute Of Medical Sciences and SUM Hospital, Bhubaneswar, Odisha, India.
Department of Pathology, Institute Of Medical Sciences and SUM Hospital, Bhubaneswar, Odisha, India.
出版信息
Int J Surg Case Rep. 2020;77:9-11. doi: 10.1016/j.ijscr.2020.10.058. Epub 2020 Oct 22.
BACKGROUND
Warthin-like variant of Papillary thyroid carcinoma (WLPTC) is an uncommon variant of PTC. They resemble Warthin tumour of salivary gland. Microscopically the tumour shows presence of papillae lined by oncocytic cells with typical nuclear features of PTC. The stalks of papillae were filled up with lymphoplasmacytic cells. WLPTC have good prognosis.
CASE REPORT
A 45-year-old lady presented with thyromegaly. She underwent total thyroidectomy with bilateral selective neck dissection (level II - level VI). Her final histopathology report was WLPTC, Right lobe with lymph nodal metastasis. Post-operatively, she received I131 radio-iodine therapy. She is under follow-up for last four years and is doing well.
CONCLUSION
Diagnosing WLPTC, a rare variant of PTC can be challenging. Definitive diagnosis helps in management.
背景
甲状腺乳头状癌的沃辛样变异型（WLPTC）是一种罕见的甲状腺乳头状癌变异型。它们类似于唾液腺的沃辛瘤。显微镜下，肿瘤可见由嗜酸性细胞衬覆的乳头，具有典型的甲状腺乳头状癌核特征。乳头的柄部充满淋巴细胞和浆细胞。WLPTC预后良好。
病例报告
一名45岁女性因甲状腺肿大就诊。她接受了全甲状腺切除术及双侧选择性颈淋巴结清扫术（II区至VI区）。她的最终组织病理学报告为WLPTC，右叶伴淋巴结转移。术后，她接受了I131放射性碘治疗。她在过去四年中一直处于随访中，情况良好。
结论
诊断WLPTC这种罕见的甲状腺乳头状癌变异型可能具有挑战性。明确诊断有助于治疗管理。
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