Reddy Allam P, Ramakrishnan Ramachandran, Narasimhan Murali
Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India.
J Family Med Prim Care. 2024 Nov;13(11):5374-5377. doi: 10.4103/jfmpc.jfmpc_569_24. Epub 2024 Nov 18.
Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease with various manifestations in the skin and several other organs. Subacute cutaneous lupus erythematosus may present with annular and psoriasiform lesions. There have been case reports of pustular lesions in SLE. Herein, we describe a known case of SLE, who developed pustular and crusted lesions which complicated the course of the disease. We considered Acute Generalised Exanthematous Pustulosis, Subcorneal Pustular Dermatosis, Pustular Psoriasis, Pustular Vasculitis, and Pustular Folliculitis as our initial differential diagnosis. A potassium hydroxide mount from crusted lesions showed scabies mites. With these findings, a diagnosis of SLE complicated with crusted scabies was made. She was managed with multiple systemic immunosuppressant and antiscabetic measures following which clinical improvement was seen with remission of her lesions.
系统性红斑狼疮(SLE)是一种自身免疫性疾病的典型代表,在皮肤和其他多个器官有多种表现。亚急性皮肤型红斑狼疮可能表现为环形和银屑病样皮损。有关于SLE出现脓疱性皮损的病例报告。在此,我们描述一例已知的SLE患者,该患者出现脓疱和结痂性皮损,使病情复杂化。我们最初的鉴别诊断考虑了急性泛发性脓疱性银屑病、角层下脓疱性皮肤病、脓疱型银屑病、脓疱性血管炎和脓疱性毛囊炎。结痂性皮损的氢氧化钾涂片显示有疥螨。基于这些发现,诊断为SLE合并结痂性疥疮。对她采取了多种全身免疫抑制和抗疥疮措施,之后皮损缓解,临床症状改善。