• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

系统性红斑狼疮中的脓疱性和结痂性病变：一例报告。

Pustular and crusted lesions in systemic lupus erythematosus: A case report.

作者信息

Reddy Allam P, Ramakrishnan Ramachandran, Narasimhan Murali

机构信息

Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2024 Nov;13(11):5374-5377. doi: 10.4103/jfmpc.jfmpc_569_24. Epub 2024 Nov 18.

DOI:10.4103/jfmpc.jfmpc_569_24
PMID:39722975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11668402/
Abstract

Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease with various manifestations in the skin and several other organs. Subacute cutaneous lupus erythematosus may present with annular and psoriasiform lesions. There have been case reports of pustular lesions in SLE. Herein, we describe a known case of SLE, who developed pustular and crusted lesions which complicated the course of the disease. We considered Acute Generalised Exanthematous Pustulosis, Subcorneal Pustular Dermatosis, Pustular Psoriasis, Pustular Vasculitis, and Pustular Folliculitis as our initial differential diagnosis. A potassium hydroxide mount from crusted lesions showed scabies mites. With these findings, a diagnosis of SLE complicated with crusted scabies was made. She was managed with multiple systemic immunosuppressant and antiscabetic measures following which clinical improvement was seen with remission of her lesions.

摘要

系统性红斑狼疮（SLE）是一种自身免疫性疾病的典型代表，在皮肤和其他多个器官有多种表现。亚急性皮肤型红斑狼疮可能表现为环形和银屑病样皮损。有关于SLE出现脓疱性皮损的病例报告。在此，我们描述一例已知的SLE患者，该患者出现脓疱和结痂性皮损，使病情复杂化。我们最初的鉴别诊断考虑了急性泛发性脓疱性银屑病、角层下脓疱性皮肤病、脓疱型银屑病、脓疱性血管炎和脓疱性毛囊炎。结痂性皮损的氢氧化钾涂片显示有疥螨。基于这些发现，诊断为SLE合并结痂性疥疮。对她采取了多种全身免疫抑制和抗疥疮措施，之后皮损缓解，临床症状改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/630040f52e45/JFMPC-13-5374-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/4682874db806/JFMPC-13-5374-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/7dbad5956227/JFMPC-13-5374-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/49ae58813310/JFMPC-13-5374-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/acb1b86e679a/JFMPC-13-5374-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/630040f52e45/JFMPC-13-5374-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/4682874db806/JFMPC-13-5374-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/7dbad5956227/JFMPC-13-5374-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/49ae58813310/JFMPC-13-5374-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/acb1b86e679a/JFMPC-13-5374-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0121/11668402/630040f52e45/JFMPC-13-5374-g005.jpg

相似文献

1
Pustular and crusted lesions in systemic lupus erythematosus: A case report.系统性红斑狼疮中的脓疱性和结痂性病变：一例报告。
J Family Med Prim Care. 2024 Nov;13(11):5374-5377. doi: 10.4103/jfmpc.jfmpc_569_24. Epub 2024 Nov 18.
2
Annular pustular crusted plaques as unusual cutaneous presentation of systemic lupus erythematosus.环状脓疱结痂性斑块作为系统性红斑狼疮不寻常的皮肤表现。
Clin Case Rep. 2023 Jun 28;11(7):e7475. doi: 10.1002/ccr3.7475. eCollection 2023 Jul.
3
Crusted scabies in systematic lupus erythematosus: a case report.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1993 Feb;26(1):44-50.
4
Chronic annular pustular psoriasis resembling subcorneal pustular dermatosis: A case report.类似角层下脓疱性皮肤病的慢性环状脓疱性银屑病：一例报告
SAGE Open Med Case Rep. 2019 Jun 20;7:2050313X19857392. doi: 10.1177/2050313X19857392. eCollection 2019.
5
Rowell Syndrome in Nigeria: Systemic Lupus Erythematosus Presenting as Recurrent Erythema Multiforme in a Young Woman.尼日利亚的罗威尔综合征：一名年轻女性中表现为复发性多形红斑的系统性红斑狼疮
Acta Dermatovenerol Croat. 2019 Sep;27(3):200-201.
6
Initiation of hydroxychloroquine therapy during pregnancy can cause adverse effects and alter pregnancy outcomes: A case of acute generalised exanthematous pustulosis induced by hydroxychloroquine in a patient with systemic lupus erythematosus.羟氯喹治疗的启动可能会在妊娠期导致不良影响并改变妊娠结局：系统性红斑狼疮患者因羟氯喹致急性泛发性发疹性脓疱病 1 例。
Mod Rheumatol Case Rep. 2023 Jun 19;7(2):373-377. doi: 10.1093/mrcr/rxac089.
7
Suspected inflammatory rheumatic diseases in patients presenting with skin rashes.疑似以皮疹为表现的炎症性风湿性疾病。
Best Pract Res Clin Rheumatol. 2019 Aug;33(4):101440. doi: 10.1016/j.berh.2019.101440. Epub 2019 Oct 1.
8
A Case of Ceftriaxone-Induced Acute Generalized Exanthematous Pustulosis/Generalized Pustular Psoriasis Overlap.1例头孢曲松所致急性泛发性脓疱性银屑病/脓疱型银屑病重叠病例
Case Rep Dermatol. 2018 Mar 27;10(1):69-75. doi: 10.1159/000488076. eCollection 2018 Jan-Apr.
9
Generalized pustular psoriasis induced by systemic steroid dose reduction.系统性类固醇剂量减少诱发的泛发性脓疱型银屑病。
An Bras Dermatol. 2016 Sep-Oct;91(5):664-666. doi: 10.1590/abd1806-4841.20163804.
10
Pustular skin disorders: diagnosis and treatment.脓疱性皮肤病：诊断与治疗
Am J Clin Dermatol. 2002;3(6):389-400. doi: 10.2165/00128071-200203060-00003.

本文引用的文献

1
Annular pustular crusted plaques as unusual cutaneous presentation of systemic lupus erythematosus.环状脓疱结痂性斑块作为系统性红斑狼疮不寻常的皮肤表现。
Clin Case Rep. 2023 Jun 28;11(7):e7475. doi: 10.1002/ccr3.7475. eCollection 2023 Jul.
2
Subcorneal pustular dermatosis: Comprehensive review and report of a case presenting during pregnancy.角层下脓疱性皮肤病：孕期病例的综合回顾与报告
Int J Womens Dermatol. 2020 Feb 20;6(3):131-136. doi: 10.1016/j.ijwd.2020.02.003. eCollection 2020 Jun.
3
Generalized pustular psoriasis complicated with bullous pemphigoid.
Int J Dermatol. 2019 Mar;58(3):e66-e67. doi: 10.1111/ijd.14332. Epub 2018 Dec 5.
4
Generalized pustular psoriasis - a model disease for specific targeted immunotherapy, systematic review.泛发性脓疱型银屑病-特异性靶向免疫治疗的典范疾病，系统评价。
Exp Dermatol. 2018 Oct;27(10):1067-1077. doi: 10.1111/exd.13699. Epub 2018 Jul 20.
5
European guideline for the management of scabies.欧洲疥疮管理指南。
J Eur Acad Dermatol Venereol. 2017 Aug;31(8):1248-1253. doi: 10.1111/jdv.14351. Epub 2017 Jun 22.
6
Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis.表现为急性泛发性脓疱性皮病的严重药物不良反应中IL36RN的罕见变异。
J Invest Dermatol. 2013 Jul;133(7):1904-7. doi: 10.1038/jid.2013.44. Epub 2013 Jan 28.
7
Crusted scabies: clinical and immunological findings in seventy-eight patients and a review of the literature.结痂性疥疮：78例患者的临床和免疫学发现及文献综述
J Infect. 2005 Jun;50(5):375-81. doi: 10.1016/j.jinf.2004.08.033.
8
[Crusted scabies in Dakar apropos of 11 cases seen in a year].[达喀尔的结痂性疥疮：一年内所见11例报告]
Dakar Med. 1999;44(2):243-5.
9
Histocompatibility (HLA) antigens in Egyptians with two parasitic skin diseases (scabies and leishmaniasis).患有两种寄生虫性皮肤病（疥疮和利什曼病）的埃及人的组织相容性（HLA）抗原
J Egypt Soc Parasitol. 1990 Dec;20(2):565-72.
10
Crusted scabies: alias Norwegian scabies.
Int J Dermatol. 1976 Dec;15:747-8. doi: 10.1111/j.1365-4362.1976.tb00173.x.