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独立斜外侧腰椎椎间融合术(OLIF)后椎间融合器对终板塌陷的影响:基于有限元分析和力学实验

The effects of cage on endplate collapse after stand-alone OLIF: based on finite element analysis and mechanics experiments.

作者信息

Li Hao, Liu Jiarui, Cui Huifei, Shen Nana, Wu Futong, Zhang Zhihao, Zhu Zhongze, Qiu Chensheng, Xiang Hongfei

机构信息

Department of Spine Surgery, The Affiliated Hospital of Qingdao University, Qindao, China.

Department of Spinal Surgery, Zibo First Hospital, Zibo, China.

出版信息

Front Bioeng Biotechnol. 2024 Dec 10;12:1508385. doi: 10.3389/fbioe.2024.1508385. eCollection 2024.

Abstract

BACKGROUND

Lumbar degenerative diseases are an important factor in disability worldwide, and they are also common among the elderly population. Stand-Alone Oblique Lumbar Interbody Fusion (Stand-Alone OLIF) is a novel surgical approach for treating lumbar degenerative diseases. However, long-term follow-up after surgery has revealed the risk of endplate collapse associated with Stand-Alone OLIF procedures. This study aimed to investigate the effect of the cage factor on endplate collapse after Stand-Alone OLIF.

METHODS

Finite element (FE) models and calf lumbar functional units were established separately and used to simulate Stand-Alone OLIF surgery. On the L5 endplate of the FE model and the calf lumbar functional unit, 12 cage positions from anterior to posterior, 16 cage inclination angles from 0° to 15°, and 4 cage heights were selected to simulate surgical models with different cage positions. Compression loads of 400N were applied to the upper surface of the superior vertebral body of the cage, and 10Nm torques in four directions were used to simulate four different physiological movements of the lumbar spine: flexion, extension, lateral curvature and torsion, in order to compare the range of motion of the surgical segment and the endplate stress.

RESULTS

When the cage is placed closer to the anterior and posterior edges of the endplate and when the height of the cage exceeds 12mm, the intervertebral range of motion at the surgical segment is greater and the stress on the endplate is higher during various lumbar spine activities. When the cage is inclined at an angle within 15°, there are no significant differences in the corresponding endplate stress and the range of motion.

CONCLUSION

For Stand-Alone OLIF surgery, inserting the cage in the central anterior-posterior position of the intervertebral space and selecting a cage with a height not exceeding 12 mm can reduce the stress on the endplate after surgery, which is more conducive to the stability of the lumbar spine postoperatively and reduces the risk of postoperative endplate collapse. The inclination angle of the cage placement does not significantly affect postoperative endplate stress or lumbar stability.

摘要

背景

腰椎退行性疾病是导致全球残疾的一个重要因素,在老年人群中也很常见。独立斜外侧腰椎椎间融合术(Stand-Alone OLIF)是一种治疗腰椎退行性疾病的新型手术方法。然而,手术后的长期随访揭示了与Stand-Alone OLIF手术相关的终板塌陷风险。本研究旨在探讨椎间融合器因素对Stand-Alone OLIF术后终板塌陷的影响。

方法

分别建立有限元(FE)模型和小牛腰椎功能单元,并用于模拟Stand-Alone OLIF手术。在FE模型和小牛腰椎功能单元的L5终板上,从前到后选择12个椎间融合器位置、从0°到15°选择16个椎间融合器倾斜角度以及4种椎间融合器高度,以模拟不同椎间融合器位置的手术模型。在椎间融合器上位椎体的上表面施加400N的压缩载荷,并使用四个方向的10Nm扭矩来模拟腰椎的四种不同生理运动:前屈、后伸、侧屈和扭转,以便比较手术节段的活动范围和终板应力。

结果

当椎间融合器放置在更靠近终板前后边缘的位置,且椎间融合器高度超过12mm时,手术节段的椎间活动范围更大,并且在各种腰椎活动期间终板上的应力更高。当椎间融合器倾斜角度在15°以内时,相应的终板应力和活动范围没有显著差异。

结论

对于Stand-Alone OLIF手术,将椎间融合器插入椎间隙的中央前后位置并选择高度不超过12mm的椎间融合器,可以降低术后终板上的应力,这更有利于术后腰椎的稳定性,并降低术后终板塌陷的风险。椎间融合器放置的倾斜角度对术后终板应力或腰椎稳定性没有显著影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/87a1/11669059/b8c5aab688fb/fbioe-12-1508385-g001.jpg

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