• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Novel epigenetic cross-talk down-regulates kidney fibrosis after injury.新型表观遗传相互作用可下调损伤后的肾纤维化。
Mol Ther. 2025 Jan 8;33(1):14-15. doi: 10.1016/j.ymthe.2024.12.029. Epub 2024 Dec 25.
2
Netrin-1 regulates colon-kidney cross talk through suppression of IL-6 function in a mouse model of DSS-colitis.Netrin-1 通过抑制 DSS 结肠炎小鼠模型中的 IL-6 功能来调节结肠-肾脏通讯。
Am J Physiol Renal Physiol. 2013 May 1;304(9):F1187-97. doi: 10.1152/ajprenal.00702.2012. Epub 2013 Feb 27.
3
Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis.靶向血管内皮细胞-周细胞相互作用抑制 VEGF 受体信号通路可减轻肾脏微血管稀疏和纤维化。
Am J Pathol. 2011 Feb;178(2):911-23. doi: 10.1016/j.ajpath.2010.10.012.
4
Myofibroblasts acquire retinoic acid-producing ability during fibroblast-to-myofibroblast transition following kidney injury.肌成纤维细胞在肾损伤后由成纤维细胞向肌成纤维细胞转化过程中获得产生视黄酸的能力。
Kidney Int. 2019 Mar;95(3):526-539. doi: 10.1016/j.kint.2018.10.017. Epub 2019 Jan 17.
5
Cross talk between lysine methyltransferase Smyd2 and TGF-β-Smad3 signaling promotes renal fibrosis in autosomal dominant polycystic kidney disease.赖氨酸甲基转移酶 Smyd2 与 TGF-β-Smad3 信号转导之间的串扰促进常染色体显性多囊肾病中的肾纤维化。
Am J Physiol Renal Physiol. 2022 Aug 1;323(2):F227-F242. doi: 10.1152/ajprenal.00452.2021. Epub 2022 Jun 27.
6
Tubular GM-CSF Promotes Late MCP-1/CCR2-Mediated Fibrosis and Inflammation after Ischemia/Reperfusion Injury.管状 GM-CSF 促进缺血/再灌注损伤后晚期 MCP-1/CCR2 介导的纤维化和炎症反应。
J Am Soc Nephrol. 2019 Oct;30(10):1825-1840. doi: 10.1681/ASN.2019010068. Epub 2019 Jul 17.
7
Polyploid tubular cells initiate a TGF-β1 controlled loop that sustains polyploidization and fibrosis after acute kidney injury.多倍体管状细胞启动 TGF-β1 控制的循环，在急性肾损伤后维持多倍体化和纤维化。
Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C849-C861. doi: 10.1152/ajpcell.00081.2023. Epub 2023 Aug 29.
8
Epigenetic therapeutics attenuate kidney injury and fibrosis by restoring the expression of epigenetically reprogrammed fibrogenic genes and signaling pathways.表观遗传学疗法通过恢复表观遗传重编程的纤维化基因和信号通路的表达来减轻肾损伤和纤维化。
Eur J Pharm Sci. 2025 Jan 1;204:106977. doi: 10.1016/j.ejps.2024.106977. Epub 2024 Nov 29.
9
The roles of cross-talk epigenetic patterns in Arabidopsis thaliana.拟南芥中串扰表观遗传模式的作用。
Brief Funct Genomics. 2016 Jul;15(4):278-87. doi: 10.1093/bfgp/elv025. Epub 2015 Jul 2.
10
Epigenetic Regulation in Kidney Transplantation.肾移植中的表观遗传调控。
Front Immunol. 2022 Apr 8;13:861498. doi: 10.3389/fimmu.2022.861498. eCollection 2022.

本文引用的文献

1
Hypermethylation and suppression of microRNA219a-2 activates the ALDH1L2/GSH/PAI-1 pathway for fibronectin degradation in renal fibrosis.微小RNA219a-2的高甲基化和抑制激活了醛脱氢酶1L2/谷胱甘肽/纤溶酶原激活物抑制因子-1途径，导致肾纤维化中纤连蛋白降解。
Mol Ther. 2025 Jan 8;33(1):249-262. doi: 10.1016/j.ymthe.2024.09.020. Epub 2024 Sep 17.
2
Chromatin and noncoding RNA-mediated mechanisms of gastric tumorigenesis.染色质和非编码 RNA 介导的胃癌发生机制。
Exp Mol Med. 2023 Jan;55(1):22-31. doi: 10.1038/s12276-023-00926-0. Epub 2023 Jan 19.
3
Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis.组蛋白修饰和非编码 RNA：相互表观遗传调控及其在发病机制中的作用。
Int J Mol Sci. 2022 May 22;23(10):5801. doi: 10.3390/ijms23105801.
4
Molecular mechanisms of transgenerational epigenetic inheritance.跨代表观遗传遗传的分子机制。
Nat Rev Genet. 2022 Jun;23(6):325-341. doi: 10.1038/s41576-021-00438-5. Epub 2022 Jan 4.
5
Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health.跨代遗传：父母的表观遗传和遗传信息如何影响后代的健康。
Hum Reprod Update. 2019 Sep 11;25(5):518-540. doi: 10.1093/humupd/dmz017.
6
Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion.抑制纤连蛋白聚合可减轻缺血再灌注引起的肾损伤。
Am J Physiol Renal Physiol. 2019 Jun 1;316(6):F1293-F1298. doi: 10.1152/ajprenal.00117.2019. Epub 2019 Apr 24.
7
Validation of differentially methylated microRNAs identified from an epigenome-wide association study; Sanger and next generation sequencing approaches.从全表观基因组关联研究中鉴定出的差异甲基化微小RNA的验证；桑格测序法和新一代测序法
BMC Res Notes. 2018 Oct 29;11(1):767. doi: 10.1186/s13104-018-3872-x.
8
Transgenerational Epigenetic Inheritance.跨代表观遗传学遗传。
Annu Rev Genet. 2018 Nov 23;52:21-41. doi: 10.1146/annurev-genet-120417-031404. Epub 2018 Aug 30.
9
Emerging roles of non-coding RNAs in epigenetic regulation.非编码 RNA 在表观遗传调控中的新兴作用。
Sci China Life Sci. 2016 Mar;59(3):227-35. doi: 10.1007/s11427-016-5010-0. Epub 2016 Jan 29.
10
Environmental stress and epigenetic transgenerational inheritance.环境应激与表观遗传的跨代遗传
BMC Med. 2014 Sep 5;12:153. doi: 10.1186/s12916-014-0153-y.

Novel epigenetic cross-talk down-regulates kidney fibrosis after injury.

作者信息

Sheikh-Hamad David

机构信息

Division of Nephrology and Selzman Institute for Kidney Health, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Center for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey VA Medical Center, Houston, TX 77030, USA.

出版信息

Mol Ther. 2025 Jan 8;33(1):14-15. doi: 10.1016/j.ymthe.2024.12.029. Epub 2024 Dec 25.

DOI:10.1016/j.ymthe.2024.12.029
PMID:39724909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11764859/
Abstract
摘要