Iakovakis Tilemahos, Drakopanagiotakis Fotios, Tirikidou Efterpi, Giatromanolaki Alexandra, Kouroupi Mary, Georgakopoulou Vasiliki E, Steiropoulos Paschalis
Department of Respiratory Medicine, School of Medicine, Democritus University of Thrace, Alexandroupolis, GRC.
Department of Pathology, University General Hospital of Alexandroupolis, Alexandroupolis, GRC.
Cureus. 2024 Nov 25;16(11):e74450. doi: 10.7759/cureus.74450. eCollection 2024 Nov.
Recurrent respiratory papillomatosis (RRP) is a challenging disease to manage, due to its highly recurring nature and the lack of a definitive treatment. It is characterized by the presence of benign papillomatous lesions caused by the human papillomavirus (HPV), which can pose a threat to the patient's airway patency and restrict their breathing ability. We present the case of a 64-year-old patient with a history of papillomas in the trachea and bronchi, treated with endobronchial cryotherapy. However, tracheal and bronchial papillomas recurred 10 years after the initial treatment and two years after the diagnosis of prostate cancer and hormonal therapy. We also engage in a discussion of the clinical and radiological features of RRP.
复发性呼吸道乳头状瘤病（RRP）是一种难以管理的疾病，因其具有高度复发性且缺乏明确的治疗方法。它的特征是存在由人乳头瘤病毒（HPV）引起的良性乳头状瘤病变，这可能对患者的气道通畅构成威胁并限制其呼吸能力。我们报告一例64岁有气管和支气管乳头状瘤病史的患者，接受了支气管内冷冻治疗。然而，气管和支气管乳头状瘤在初始治疗后10年以及前列腺癌诊断和激素治疗后两年复发。我们还对RRP的临床和放射学特征进行了讨论。
