Zhu Mengyi, Zhang Jiarui, Liang Diefei, Qiu Junxiong, Fu Yuan, Zeng Zhaopei, Han Jingjun, Zheng Junmeng, Lin Liling
Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Br J Pain. 2024 Dec 24:20494637241310697. doi: 10.1177/20494637241310697.
Chronic pain poses a significant public health challenge. We present the global and regional data on Prevalence, Incidence and Years Lived with Disability (YLDs) for Chronic pain from the Global burden of disease (GBD) study 2019 data and analyze their associations with Socio-demographic index (SDI), age, and gender, and the future trends from 2020 to 2035.
Regional trends in the burden of chronic pain and its association with age, gender, and SDI were assessed from 1990 to 2019. Joinpoint analysis was employed to describe trends in chronic pain burden across different SDI regions. Additionally, the Bayesian Age-Period-Cohort model (BAPC) was used for predicting future trends. Age-standardized rates (ASRs) of prevalence, incidence, and YLDs were employed to quantify the burden of chronic pain.
Between 1990 and 2019, a significant increase was observed in global prevalence and YLDs rates of chronic pain. Higher rates were found among females, whereas a faster rise was noted among males. Notably, Low Back Pain (LBP) and Migraine accounted for predominant YLDs globally, particularly among those aged 75 and above. A notable prevalence of Tension-type Headache (TTH) was observed among younger populations. Furthermore, ASRs for chronic pain were highest in high-SDI regions. Projections suggest an increase in headache ASRs globally for both genders from 2020 to 2035.
From 1990 to 2019, the global burden of chronic pain increased significantly, with projections indicating a continued rise in headache burden over the next 15 years, underscoring the need for heightened attention to these issues.
慢性疼痛构成了一项重大的公共卫生挑战。我们展示了来自《2019年全球疾病负担（GBD）研究》中关于慢性疼痛的患病率、发病率和残疾生存年数（YLDs）的全球和区域数据，并分析了它们与社会人口指数（SDI）、年龄和性别的关联，以及2020年至2035年的未来趋势。
评估了1990年至2019年慢性疼痛负担的区域趋势及其与年龄、性别和SDI的关联。采用Joinpoint分析来描述不同SDI区域慢性疼痛负担的趋势。此外，使用贝叶斯年龄-时期-队列模型（BAPC）预测未来趋势。采用患病率、发病率和YLDs的年龄标准化率（ASRs）来量化慢性疼痛的负担。
1990年至2019年期间，全球慢性疼痛的患病率和YLDs率显著增加。女性的患病率更高，而男性的上升速度更快。值得注意的是，全球范围内，腰痛（LBP）和偏头痛占主要的YLDs，尤其是在75岁及以上人群中。在年轻人群中观察到紧张型头痛（TTH）的患病率较高。此外，高SDI区域的慢性疼痛ASRs最高。预测表明，2020年至2035年全球范围内男女头痛的ASRs均会增加。
1990年至2019年，全球慢性疼痛负担显著增加，预测表明未来15年头痛负担将持续上升，这凸显了对这些问题加强关注的必要性。
