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电子烟对口腔健康的影响——一篇叙述性综述

The Impact of E-Cigarettes on Oral Health-A Narrative Review.

作者信息

Cichońska Dominika, Kusiak Aida, Goniewicz Maciej L

机构信息

Department of Periodontology and Oral Mucosa Diseases, Medical University of Gdańsk, 80-208 Gdańsk, Poland.

Department of Health Behavior, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, NY 14203, USA.

出版信息

Dent J (Basel). 2024 Dec 10;12(12):404. doi: 10.3390/dj12120404.

DOI:10.3390/dj12120404
PMID:39727461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11675017/
Abstract

: Electronic cigarettes (e-cigarettes) are commonly used by former smokers as an alternative product to conventional cigarettes and also by young adults and adolescents to deliver nicotine. E-cigarettes are thought to be a less harmful and more socially acceptable alternative to tobacco smoking; however, their long-term effects on health, including oral health, are currently unknown. : A literature search for relevant papers indexed in the literature from 2016 to 2023 was conducted using the PubMed, Scopus, and Google Scholar databases. In our paper, we included clinical trials and both in vivo and in vitro research concerning the impact of e-cigarettes on oral health. : E-cigarettes impact the oral cavity, which is directly exposed to inhaled chemicals present in e-cigarette aerosols. The use of e-cigarettes has been linked to teeth discoloration and dental caries, promoting the development of periodontal diseases and causing oral mucosa lesions, including oral cancer. E-cigarette aerosols might also negatively affect the oral microbiome by suppressing the growth of commensal bacteria and increasing the population of bacteria responsible for developing numerous oral disorders. E-cigarettes also impact saliva composition and its properties, including reducing saliva's antibacterial and antioxidant properties, which may subsequently lead to the promotion of oral diseases. : The outcomes suggest that e-cigarette usage may cause the development of oral diseases, however further longitudinal studies of a larger and homogenous group of e-cigarette users are required.

摘要

电子烟通常被曾经吸烟的人用作传统香烟的替代产品,也被年轻人和青少年用来摄取尼古丁。电子烟被认为是一种比吸烟危害更小且在社会上更易被接受的替代品;然而,它们对健康的长期影响,包括对口腔健康的影响,目前尚不清楚。

使用PubMed、Scopus和谷歌学术数据库对2016年至2023年文献中索引的相关论文进行了文献检索。在我们的论文中,我们纳入了关于电子烟对口腔健康影响的临床试验以及体内和体外研究。

电子烟会影响口腔,口腔会直接接触到电子烟烟雾中吸入的化学物质。使用电子烟与牙齿变色和龋齿有关,会促进牙周疾病的发展并导致口腔黏膜病变,包括口腔癌。电子烟烟雾还可能通过抑制共生细菌的生长和增加导致多种口腔疾病的细菌数量,对口腔微生物群产生负面影响。电子烟还会影响唾液成分及其特性,包括降低唾液的抗菌和抗氧化特性,这可能随后导致口腔疾病的加剧。

研究结果表明,使用电子烟可能会导致口腔疾病的发生,然而,需要对更大规模且同质化的电子烟使用者群体进行进一步的纵向研究。

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引用本文的文献

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Dent J (Basel). 2025 Mar 10;13(3):119. doi: 10.3390/dj13030119.

本文引用的文献

1
The impact of electronic and conventional cigarettes on periodontal health-a systematic review and meta-analysis.电子和传统香烟对牙周健康的影响:系统评价和荟萃分析。
Clin Oral Investig. 2023 Sep;27(9):4911-4928. doi: 10.1007/s00784-023-05162-4. Epub 2023 Aug 1.
2
e-Cigarettes and Oral Cancer: what do we know so far?电子烟与口腔癌:目前我们了解多少?
Br J Oral Maxillofac Surg. 2023 Jun;61(5):380-382. doi: 10.1016/j.bjoms.2023.03.013. Epub 2023 Apr 3.
3
The mediating roles of the oral microbiome in saliva and subgingival sites between e-cigarette smoking and gingival inflammation.电子烟吸烟与牙龈炎症之间口腔微生物组在唾液和龈下部位的中介作用。
BMC Microbiol. 2023 Feb 2;23(1):35. doi: 10.1186/s12866-023-02779-z.
4
Comparison of periodontal status and salivary IL-15 and -18 levels in cigarette-smokers and individuals using electronic nicotine delivery systems.比较吸烟和使用电子尼古丁传送系统人群的牙周状况和唾液中白细胞介素-15 和 -18 水平。
BMC Oral Health. 2022 Dec 30;22(1):655. doi: 10.1186/s12903-022-02700-6.
5
Effect of Cigarette and E-Cigarette Smoke Condensates on Biofilm Formation and Gene Expression.香烟和电子烟烟雾冷凝物对生物膜形成和基因表达的影响。
Int J Environ Res Public Health. 2022 Apr 12;19(8):4626. doi: 10.3390/ijerph19084626.
6
E-Cigarette Aerosol Exposure Favors the Growth and Colonization of Oral Streptococcus mutans Compared to Commensal Streptococci.电子烟气溶胶暴露比共栖链球菌更有利于口腔变异链球菌的生长和定植。
Microbiol Spectr. 2022 Apr 27;10(2):e0242121. doi: 10.1128/spectrum.02421-21. Epub 2022 Apr 4.
7
Influence of Electronic Cigarettes on Selected Physicochemical Properties of Saliva.电子烟对唾液某些理化性质的影响。
Int J Environ Res Public Health. 2022 Mar 11;19(6):3314. doi: 10.3390/ijerph19063314.
8
Effect of electronic cigarette and tobacco smoking on the human saliva microbial community.电子烟和吸烟对人体唾液微生物群落的影响。
Braz J Microbiol. 2022 Jun;53(2):991-1000. doi: 10.1007/s42770-022-00721-5. Epub 2022 Mar 1.
9
A pilot investigation into the influence of electronic cigarettes on oral bacteria.电子烟对口腔细菌影响的初步调查。
Postepy Dermatol Alergol. 2021 Dec;38(6):1092-1098. doi: 10.5114/ada.2020.100335. Epub 2022 Jan 7.
10
Comparative Effects of E-Cigarette Aerosol on Periodontium of Periodontitis Patients.电子烟烟雾对牙周炎患者牙周组织的比较影响
Front Oral Health. 2021 Sep 7;2:729144. doi: 10.3389/froh.2021.729144. eCollection 2021.