Tomljenović Robert, Košec Andro, Kalogjera Livije, Ćelap Ivana, Marijančević Domagoj, Vagić Davor
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Sestre Milosrdnice, Vinogradska Cesta 29, 10000 Zagreb, Croatia.
School of Medicine, University of Zagreb, Šalata 2, 10000 Zagreb, Croatia.
Audiol Res. 2024 Dec 9;14(6):1093-1104. doi: 10.3390/audiolres14060090.
: This study examines the potential associations between salivary cortisol concentrations and subjective stress test scores in healthy individuals subjected to sound-related, psychological, and physical stressors. : This study employed a single-center observational cross-sectional design, with a sample size of 36 subjects recruited from a tertiary referral audiology center. Between 2023 and 2024, the study recruited subjects with normal hearing, baseline salivary cortisol levels, and subjective stress levels. The participants were requested to complete an STAI-Y1 questionnaire and provide salivary cortisol samples before and following exposure to sound-related, psychological, and physical stress tests. : Exposure to psychological and physical stressors significantly increased STAI-Y1 scores (Friedman's test, χ = 57.118, df = 2, = 0.377). This increase was greater than that observed in response to loud, favorite music (Friedman's test, χ = 57.118, df = 2, < 0.0001). The salivary cortisol concentration significantly increased in all three provocation tests (Friedman's test, χ = 95.264, df = 5, < 0.0001). Furthermore, there is no significant difference in salivary cortisol concentrations between the three pre-test and post-test measurement intervals, indicating a comparable stress-inducing pattern regardless of the nature of the stimulus (Friedman's test, χ = 95.264, df = 5, > 0.05). : Exposure to loud favorite music increases salivary cortisol concentrations, as does acute physical and psychological stress. Interestingly, unlike psychological and physical stress, loud music was not objectively perceived as stress, which may mask the physiological signs of stress, potentially increasing the risk of both acute and chronic stress-related health outcomes.
本研究考察了健康个体在遭受与声音相关、心理和身体应激源时，唾液皮质醇浓度与主观应激测试得分之间的潜在关联。本研究采用单中心观察性横断面设计，样本量为36名受试者，从一家三级转诊听力中心招募。在2023年至2024年期间，该研究招募了听力正常、基线唾液皮质醇水平和主观应激水平的受试者。参与者被要求完成一份状态特质焦虑问卷（STAI-Y1），并在暴露于与声音相关、心理和身体应激测试之前和之后提供唾液皮质醇样本。暴露于心理和身体应激源会显著提高STAI-Y1得分（弗里德曼检验，χ = 57.118，自由度 = 2，P = 0.377）。这种增加大于对喜欢的大声音乐的反应（弗里德曼检验，χ = 57.118，自由度 = 2，P < 0.0001）。在所有三种激发测试中，唾液皮质醇浓度均显著增加（弗里德曼检验，χ = 95.264，自由度 = 5，P < 0.0001）。此外，三次测试前和测试后测量间隔之间的唾液皮质醇浓度没有显著差异，表明无论刺激的性质如何，应激诱导模式具有可比性（弗里德曼检验，χ = 95.264，自由度 = 5，P > 0.05）。暴露于喜欢的大声音乐会增加唾液皮质醇浓度，急性身体和心理应激也是如此。有趣的是，与心理和身体应激不同，大声音乐在客观上不被视为应激，这可能会掩盖应激的生理迹象，潜在地增加急性和慢性应激相关健康结果的风险。
