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使用流体动力学加速试验评估用于可生物降解植入物的等离子体电解氧化镁合金AZ31的降解性能。

Evaluation of the Degradation Properties of Plasma Electrolytically Oxidized Mg Alloy AZ31 Using Fluid Dynamic Accelerated Tests for Biodegradable Implants.

作者信息

Saqib Muhammad, Kremmer Kerstin, Opitz Joerg, Schneider Michael, Beshchasna Natalia

机构信息

Department of Bio and Nanotechnology, Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Maria-Reiche-Strasse 2, 01109 Dresden, Germany.

Department of Electrochemistry, Fraunhofer Institute for Ceramic Technologies and Systems IKTS, Winterbergstrasse 28, 01277 Dresden, Germany.

出版信息

J Funct Biomater. 2024 Dec 3;15(12):366. doi: 10.3390/jfb15120366.

DOI:10.3390/jfb15120366
PMID:39728166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11678049/
Abstract

Magnesium alloys are promising biodegradable implant materials due to their excellent biocompatibility and non-toxicity. However, their poor corrosion resistance limits their application in vivo. Plasma electrolytic oxidation (PEO) is a powerful technique to improve the corrosion resistance of magnesium alloys. In this study, we present the accelerated degradation of PEO-treated AZ31 samples using a fluid dynamic test. The samples were prepared using different concentrations of KOH as an electrolyte along with NaSiO. The anodizing time and the biasing time were optimized to obtain the increased corrosion resistance. The analysis of the degraded samples using microscopy, SEM EDX measurements, and by calculating mass loss and corrosion rates showed a significant increase in the corrosion resistance after the polymer (Resomer© LG 855 S) coating was applied to the anodized samples. The results confirm (or convince) that PEO treatment is an effective way to improve the corrosion resistance of AZ31 magnesium alloy. The fluid dynamic test can be used as an accelerated degradation test for biodegradable alloys in simulated body fluids at a physiological temperature. The polymer coating further improves the corrosion resistance of the PEO-treated AZ31 samples.

摘要

镁合金因其优异的生物相容性和无毒性而成为很有前景的可生物降解植入材料。然而，其耐腐蚀性较差限制了它们在体内的应用。等离子体电解氧化（PEO）是一种提高镁合金耐腐蚀性的有效技术。在本研究中，我们通过流体动力学试验展示了经PEO处理的AZ31样品的加速降解情况。样品制备使用不同浓度的KOH作为电解液并添加NaSiO。对阳极氧化时间和偏置时间进行了优化以提高耐腐蚀性。使用显微镜、扫描电子显微镜能谱分析（SEM EDX）测量以及通过计算质量损失和腐蚀速率对降解后的样品进行分析，结果表明在对阳极氧化后的样品施加聚合物（Resomer© LG 855 S）涂层后，其耐腐蚀性显著提高。结果证实（或表明）PEO处理是提高AZ31镁合金耐腐蚀性的有效方法。流体动力学试验可作为在生理温度下模拟体液中可生物降解合金的加速降解试验。聚合物涂层进一步提高了经PEO处理的AZ31样品的耐腐蚀性。

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