• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

神经轴索麻醉与神经根损伤风险:一项三维体外研究

Neuraxial Anesthesia and Risk of Root Damage: A 3D Ex Vivo Study.

作者信息

Labandeyra Hipólito, Sala-Blanch Xavier, Prats-Galino Alberto, Puigdellívol-Sánchez Anna

机构信息

Laboratory of Surgical Neuroanatomy (LSNA), Human Anatomy and Embryology Unit, Faculty of Medicine and Health Sciences, Universitat de Barcelona, 08036 Barcelona, Spain.

Division of Regional Anesthesia, Anesthesiology Service, HM Delfos Hospital, 08023 Barcelona, Spain.

出版信息

NeuroSci. 2024 Dec 3;5(4):623-634. doi: 10.3390/neurosci5040044.

DOI:10.3390/neurosci5040044
PMID:39728676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11677341/
Abstract

Cauda equina nerve roots may become damaged during neuraxial anesthesia, and post-puncture headache may appear in the case of cerebrospinal fluid leakage if needle tips are deformed due to bone contact when several attempts are needed. Our aim was to verify the correlation between skin-transverse process distance (st) and skin-dural sac distance (d) for calculation of optimal angles in a free visual guide and as a reference for the maximal depth to be traversed by the needle. Randomly selected ex vivo samples ( = 10) were flexed to reproduce the position of the lumbosacral spine during spinal anesthesia. Spinal needles were inserted perpendicular to the skin either blindly or following the inferred paramedian angle corresponding to ultrasound-measured (d). After computed tomography and three-dimensional reconstruction, both (st) and (d) were measured, and the Pearson correlation index was calculated. A free 3D-PDF tool was used to illustrate the potential affectation of nerve cuffs by needles located lateral to the dural sac. Correlation between (d) and (st) was 0.84-0.93 at L4L5-L3L4 intervertebral levels, and most needle tips were located within the spinal canal, but some traversed the zone where nerve cuffs emerge. In conclusion, ultrasound may determine if a perpendicular needle insertion is viable at midline. If not, the optimal paramedian angle and maximal depth may be determined by measuring (st).

摘要

马尾神经根在椎管内麻醉期间可能会受损,若多次穿刺时因针尖端与骨质接触而变形导致脑脊液漏,则可能出现穿刺后头痛。我们的目的是验证皮肤至横突距离(st)与皮肤至硬脊膜囊距离(d)之间的相关性,以便在无视觉辅助引导下计算最佳进针角度,并作为针穿刺最大深度的参考。随机选取10个离体样本进行弯曲,以重现腰段脊柱在脊髓麻醉时的位置。将脊髓穿刺针垂直于皮肤盲目插入,或按照与超声测量的(d)相对应的旁正中进针角度插入。在计算机断层扫描和三维重建后,测量(st)和(d),并计算皮尔逊相关指数。使用一个免费的3D-PDF工具来说明位于硬脊膜囊外侧的针可能对神经袖套造成的影响。在L4L5 - L3L4椎间水平,(d)与(st)的相关性为0.84 - 0.93,大多数针尖位于椎管内,但有些则穿过了神经袖套发出的区域。总之,超声可确定在中线垂直进针是否可行。若不可行,则可通过测量(st)来确定最佳旁正中进针角度和最大深度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/e047b0139886/neurosci-05-00044-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/e80b30da4c3a/neurosci-05-00044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/a1ccc8f9e7d3/neurosci-05-00044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/ece6712e3131/neurosci-05-00044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/29a843de88cb/neurosci-05-00044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/d88bb9613f2d/neurosci-05-00044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/aee4cbd250f2/neurosci-05-00044-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/e047b0139886/neurosci-05-00044-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/e80b30da4c3a/neurosci-05-00044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/a1ccc8f9e7d3/neurosci-05-00044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/ece6712e3131/neurosci-05-00044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/29a843de88cb/neurosci-05-00044-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/d88bb9613f2d/neurosci-05-00044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/aee4cbd250f2/neurosci-05-00044-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b08/11677341/e047b0139886/neurosci-05-00044-g007.jpg

相似文献

1
Neuraxial Anesthesia and Risk of Root Damage: A 3D Ex Vivo Study.神经轴索麻醉与神经根损伤风险:一项三维体外研究
NeuroSci. 2024 Dec 3;5(4):623-634. doi: 10.3390/neurosci5040044.
2
Pythagoras and Cosines: The skin-dural sac distance and optimal angles in paramedian spinal anesthesia.
Clin Anat. 2016 Nov;29(8):1046-1052. doi: 10.1002/ca.22792. Epub 2016 Oct 6.
3
[Ultrasound imaging increases first-attempt success rate of neuraxial block in elderly patients].[超声成像提高老年患者神经轴阻滞首次尝试成功率]
Zhonghua Yi Xue Za Zhi. 2016 Nov 22;96(43):3459-3463. doi: 10.3760/cma.j.issn.0376-2491.2016.43.004.
4
Failed dural puncture during needle-through-needle combined spinal-epidural anesthesia: a case series.针内针联合脊麻-硬膜外麻醉时硬膜穿刺失败:病例系列
J Pain Res. 2019 May 17;12:1615-1619. doi: 10.2147/JPR.S178640. eCollection 2019.
5
Changes in needle maneuver space and optimal insertion site for midline neuraxial puncture with progressive age: an analysis in computed tomography scans.随着年龄增长中线椎管内穿刺针操作空间及最佳穿刺部位的变化:计算机断层扫描分析
Reg Anesth Pain Med. 2024 Dec 2;49(12):853-860. doi: 10.1136/rapm-2023-104981.
6
Optimal Point of Insertion and Needle Angle in Neuraxial Blockade Using a Midline Approach: A Study in Computed Tomography Scans of Adult Patients.中线入路行椎管内阻滞的最佳进针点和进针角度:一项成人患者 CT 扫描研究。
Reg Anesth Pain Med. 2017 Sep/Oct;42(5):600-608. doi: 10.1097/AAP.0000000000000653.
7
Incidence of dural sac puncture during neuraxial anesthesia in cats: an observational, retrospective study.猫神经轴索麻醉期间硬脊膜囊穿刺的发生率:一项观察性回顾性研究。
J Feline Med Surg. 2022 Apr;24(4):398-401. doi: 10.1177/1098612X211021292. Epub 2021 Jun 7.
8
[Post spinal headache. Its incidence following the median and paramedian techniques].[脊柱穿刺后头痛。采用正中及旁正中技术后的发生率]
Anaesthesist. 1992 Mar;41(3):137-41.
9
Postdural Puncture Headache Related to Procedure: Incidence and Risk Factors After Neuraxial Anesthesia and Spinal Procedures.硬脊膜穿破后头痛与操作相关:椎管内麻醉和脊柱操作后的发生率和危险因素。
Pain Med. 2021 Jun 4;22(6):1420-1425. doi: 10.1093/pm/pnaa437.
10
Impact of spinal needle design and approach to postdural puncture headache and spinal anesthesia failure in obstetrics.脊髓穿刺针设计及穿刺方法对产科硬膜穿刺后头痛和脊髓麻醉失败的影响
Anaesthesiol Intensive Ther. 2019;51(2):77-82. doi: 10.5114/ait.2019.86166.

本文引用的文献

1
New set of indicators with consensus definition for anaesthesia-related severe morbidity: A scoping review followed by a Delphi study.一套新的、具有共识定义的麻醉相关严重并发症指标:一项范围综述及随后的德尔菲研究。
J Clin Anesth. 2024 Dec;99:111626. doi: 10.1016/j.jclinane.2024.111626. Epub 2024 Sep 17.
2
A horizontal and perpendicular interlaminar approach for intrathecal nusinersen injection in patients with spinal muscular atrophy and scoliosis: an observational study.经皮水平和垂直入路蛛网膜下腔注射 nusinersen 治疗脊柱侧弯型脊髓性肌萎缩症患者的观察性研究。
Orphanet J Rare Dis. 2024 Jul 15;19(1):268. doi: 10.1186/s13023-024-03278-8.
3
Risk Factors in Administering Spinal Anesthesia: A Comprehensive Review.
脊髓麻醉给药的风险因素:全面综述
Cureus. 2023 Dec 4;15(12):e49886. doi: 10.7759/cureus.49886. eCollection 2023 Dec.
4
Paramedian versus midline approach of spinal anesthesia: a systematic review and meta-analysis with trial sequential analysis.旁正中与正中入路行椎管内麻醉:一项系统评价和试验序贯分析的荟萃分析。
J Anesth. 2024 Feb;38(1):65-76. doi: 10.1007/s00540-023-03281-6. Epub 2023 Nov 29.
5
Changes in needle maneuver space and optimal insertion site for midline neuraxial puncture with progressive age: an analysis in computed tomography scans.随着年龄增长中线椎管内穿刺针操作空间及最佳穿刺部位的变化:计算机断层扫描分析
Reg Anesth Pain Med. 2024 Dec 2;49(12):853-860. doi: 10.1136/rapm-2023-104981.
6
Delayed approach to postdural puncture headache.迟发性硬脊膜穿刺后头痛。
BMJ Case Rep. 2023 Sep 22;16(9):e254018. doi: 10.1136/bcr-2022-254018.
7
Comparative Effectiveness Research on Spinal versus General Anesthesia for Surgery in Older Adults.老年人脊柱麻醉与全身麻醉手术的比较效果研究。
Anesthesiology. 2023 Aug 1;139(2):211-223. doi: 10.1097/ALN.0000000000004604.
8
Ultrasound predictors of difficult spinal anesthesia: a prospective single-blind observational study.超声预测困难性椎管内麻醉:一项前瞻性单盲观察性研究。
Minerva Anestesiol. 2023 Nov;89(11):996-1002. doi: 10.23736/S0375-9393.22.16990-7. Epub 2023 Feb 21.
9
Cerebrospinal fluid fistula after combined spinal-epidural block.脊麻-硬膜外联合阻滞后发生脑脊液漏。
BMJ Case Rep. 2022 Mar 3;15(3):e247598. doi: 10.1136/bcr-2021-247598.
10
Factors predicting difficult spinal block: A single centre study.预测脊柱阻滞困难的因素:一项单中心研究。
J Anaesthesiol Clin Pharmacol. 2021 Jul-Sep;37(3):395-401. doi: 10.4103/joacp.JOACP_196_19. Epub 2021 Oct 12.