Zhang Can, Zhou Yongfei, Ming Li, Chen Lihong, Xue Minqiao, Zhang Jing, Zhang Hongyan
School of Food & Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
School of Food & Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Food Chem. 2025 Mar 30;469:142615. doi: 10.1016/j.foodchem.2024.142615. Epub 2024 Dec 23.
The inclusion of artificial food additives such as vanillin in infant formula should be strictly monitored to mitigate potential negative impacts on the dietary habits and health of infants. This raises a necessity of an accurate inspection and prompt feedback of vanillin in infant foods. In this study, colorimetric and fluorescent dual-mode assays based on CuNS/FeO@MIPs were established to detect vanillin selectively and sensitively. Quantification of vanillin could be achieved with linear detection ranges of 1-100 μM and 1-150 μM for the colorimetric and fluorescent assays respectively. The corresponding detection limits were 0.11 and 0.10 μM respectively. The CuNS/FeO@MIPs-based dual-mode assays exhibited good selectivity and stability for vanillin detection in infant formula and milk-based foods. Hence, this method can serve as a reliable tool for the cost-saving, effective and quantitative determination of vanillin in infant foods, with the potential to replace conventional instrumental analysis.
婴儿配方奶粉中香兰素等人工食品添加剂的添加应受到严格监控，以减轻对婴儿饮食习惯和健康的潜在负面影响。这就需要对婴儿食品中的香兰素进行准确检测并及时反馈。在本研究中，建立了基于CuNS/FeO@MIPs的比色和荧光双模式测定法，用于选择性和灵敏地检测香兰素。香兰素的定量分析在比色法和荧光法中的线性检测范围分别为1-100 μM和1-150 μM。相应的检测限分别为0.11和0.10 μM。基于CuNS/FeO@MIPs的双模式测定法在婴儿配方奶粉和乳基食品中对香兰素检测具有良好的选择性和稳定性。因此，该方法可作为一种可靠的工具，用于婴儿食品中香兰素的低成本、有效和定量测定，有潜力取代传统的仪器分析方法。
