Jin Jiaxuan, Yang Hedan, Ding Hui, Zheng Huiying, Zhang Xiaoli, Ge Yiping, Yang Yin, Lin Tong
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Jiangwangmiao Street 12, Xuanwu District, Nanjing, Jiangsu Province, 210042, China.
Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing, 210042, China.
Lasers Med Sci. 2024 Dec 28;40(1):1. doi: 10.1007/s10103-024-04247-0.
Traumatic scars negatively impact the patient's quality of life. Fractional 1064 nm Nd: YAG picosecond laser improves scars. However, the effect varies among individuals. This study aimed to evaluate the treatment of traumatic scars with fractional 1064 nm Nd: YAG picosecond lasers and the factors associated with its prognostication. We conducted a retrospective study with 161 patients with traumatic scars. All scars were treated using fractional 1064 nm Nd: YAG picosecond lasers. Efficacy was determined based on blinded visual evaluation using the Manchester Scar Scale (MSS) and 5-point Global Assessment Scale (GAS). The mean MSS values before and after treatments was 17.4 ± 2.7 and 13.6 ± 2.6 (P < 0.001), respectively. Color, radiance, contour, and distortion of the traumatic scars improved. (all P < 0.001). The course, location, and height of the scars, and the number of treatments and energy densities, were related to treatment responses (P < 0.05). Fractional 1064 nm Nd: YAG picosecond laser is effective for treating traumatic scars. Clinicians can predict the prognosis using multiple factors.
创伤性瘢痕对患者的生活质量有负面影响。1064纳米掺钕钇铝石榴石皮秒激光分次治疗可改善瘢痕。然而，个体之间的效果存在差异。本研究旨在评估1064纳米掺钕钇铝石榴石皮秒激光分次治疗创伤性瘢痕及其预后相关因素。我们对161例创伤性瘢痕患者进行了一项回顾性研究。所有瘢痕均采用1064纳米掺钕钇铝石榴石皮秒激光分次治疗。疗效根据使用曼彻斯特瘢痕量表（MSS）和5分整体评估量表（GAS）的盲法视觉评估来确定。治疗前后的平均MSS值分别为17.4±2.7和13.6±2.6（P<0.001）。创伤性瘢痕的颜色、光泽、轮廓和畸形均有改善（均P<0.001）。瘢痕的病程、位置、高度、治疗次数和能量密度与治疗反应相关（P<0.05）。1064纳米掺钕钇铝石榴石皮秒激光分次治疗创伤性瘢痕有效。临床医生可以使用多种因素预测预后。
