Xue Jingjing, Lyu Guorong, Li Shaohui
Department of Ultrasound, The Fujian Medical University Union Hospital, Fuzhou, China.
Department of Ultrasound, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, 362000, China.
BMC Med Imaging. 2024 Dec 27;24(1):352. doi: 10.1186/s12880-024-01530-y.
This study explored the value of stomach ultrasound reporting and data system (Su-RADS) and two-dimensional shear wave elastography (2D-SWE) in the diagnosis of benign and malignant lesions of the gastric wall, evaluating the feasibility of combining the two methods for the diagnosis of gastric wall lesions.
113 patients with gastric wall lesions were examined after oral gastric ultrasound contrast agent, and the grades of the gastric wall lesions were classified according to Su-RADS. Moreover, 2D-SWE was performed to measure the E value of the lesions. ROC curves were constructed to evaluate the diagnostic efficacy of Su-RADS, 2D-SWE and their combination for gastric wall lesions.
The cutoff values for Emean and Emax were 8.01 kPa and 11.08 kPa, respectively. The sensitivity and specificity of 2D-SWE were 70.59%, 93.67% and 85.69%, 88.61%, respectively. The diagnostic sensitivity and specificity of Su-RADS were 91.18% and 82.28%, respectively. The AUC of combination of two methods was 0.951, which was greater than that of Su-RADS (0.940) or 2D-SWE alone (0.853, 0.903), and the sensitivity and specificity were 82.35% and 94.94%. The sensitivity and specificity of the combination of the two methods for the diagnosis of malignant gastric lesions were 82.35% and 94.94%, respectively. The AUC was 0.951, and the Youden index was 0.8064. The DeLong test was used to determine the AUC between the combination of two methods and 2D-SWE was P < 0.05.
Compared with Su-RADS or 2D-SWE alone, the combination of the two methods is more effective at diagnosing of gastric wall.And improved the specificity in the diagnosis of gastric wall lesions.
本研究探讨胃超声报告和数据系统（Su-RADS）及二维剪切波弹性成像（2D-SWE）在胃壁良恶性病变诊断中的价值，评估两种方法联合诊断胃壁病变的可行性。
113例胃壁病变患者口服胃超声造影剂后进行检查，根据Su-RADS对胃壁病变进行分级。此外，采用2D-SWE测量病变的E值。构建ROC曲线，评估Su-RADS、2D-SWE及其联合诊断胃壁病变的效能。
Emean和Emax的截断值分别为8.01kPa和11.08kPa。2D-SWE的敏感度和特异度分别为70.59%、93.67%和85.69%、88.61%。Su-RADS的诊断敏感度和特异度分别为91.18%和82.28%。两种方法联合的AUC为0.951，大于单独的Su-RADS（0.940）或2D-SWE（0.853、0.903），其敏感度和特异度分别为82.35%和94.94%。两种方法联合诊断胃恶性病变的敏感度和特异度分别为82.35%和94.94%。AUC为0.951，约登指数为0.8064。采用DeLong检验确定两种方法联合与2D-SWE之间的AUC，P＜0.05。
与单独使用Su-RADS或2D-SWE相比，两种方法联合在胃壁病变诊断中更有效，且提高了胃壁病变诊断的特异度。
