Šavikin Katarina, Bigović Dubravka, Krgović Nemanja, Menković Nemanja, Nikolić Slavka, Živković Jelena
Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, 11000, Serbia.
Clinical Center of Serbia, Center for Radiology and Magnetic Resonance, Belgrade, 11000, Serbia.
Plant Foods Hum Nutr. 2024 Dec 28;80(1):21. doi: 10.1007/s11130-024-01261-z.
Cellulite is an aesthetically distressing skin condition occurring in 80-90% of females and manifesting as dimples and depressions, producing an uneven surface to the skin. Our aim was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 32 days on cellulite reduction. Twenty women aged 21-49 with a cellulite grade of 1-2 according to the Nurnberger-Muller scale were participating in the study. Ultrasonography was applied to analyze the skin structure in addition to biochemical and anthropometric parameters, which were measured before starting the treatment and after 32 days. A reduction in the thickness of the dermis with subcutaneous fat tissue, subcutaneous fat tissue alone, epidermis, and dermis with epidermis (15.02, 14.34, 21.98, and 20.94%, respectively) was noticed, while the length of the fascicles was reduced by 35.93%. Out of 20 subjects, 11 (57.9%) had edema of the dermis at the beginning of the study, which was not recorded at the end of the study. Moreover, a statistically significant increase in the tissue doppler (TD) signals was recorded in all subjects treated with two dietary supplements, indicating a better blood supply. Changes in anthropometric and biochemical parameters were not recorded. Creatinine, urea, ALT, and AST values, as indicators of kidney and liver function, remained at normal reference levels, pointing out the product's safety. The positive effect of chokeberry and tart cherry juice-based dietary supplements consumption in cellulite condition could be connected with microcirculation improvements.
橘皮组织是一种在80%至90%的女性中出现的影响美观的皮肤状况,表现为酒窝和凹陷,使皮肤表面凹凸不平。我们的目的是评估连续32天联合口服两种以黑果腺肋花楸汁和酸樱桃汁为基础的膳食补充剂对减少橘皮组织的效果。根据纽伦堡 - 米勒量表,20名年龄在21至49岁、橘皮组织等级为1至2级的女性参与了该研究。除了生化和人体测量参数外,还应用超声检查来分析皮肤结构,这些参数在治疗开始前和32天后进行测量。发现真皮与皮下脂肪组织、单独的皮下脂肪组织、表皮以及真皮与表皮的厚度均有所减少(分别为15.02%、14.34%、21.98%和20.94%),而束状带长度减少了35.93%。在20名受试者中,11名(57.9%)在研究开始时存在真皮水肿,而在研究结束时未记录到。此外,在所有接受两种膳食补充剂治疗的受试者中,组织多普勒(TD)信号有统计学意义的增加,表明血液供应改善。人体测量和生化参数未记录到变化。作为肾脏和肝脏功能指标的肌酐、尿素、谷丙转氨酶(ALT)和谷草转氨酶(AST)值保持在正常参考水平,表明该产品的安全性。食用以黑果腺肋花楸汁和酸樱桃汁为基础的膳食补充剂对橘皮组织状况的积极作用可能与微循环改善有关。