Gomez Pons Andrea, Lukens Frank J, Osagiede Osayande
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL.
ACG Case Rep J. 2024 Dec 27;12(1):e01577. doi: 10.14309/crj.0000000000001577. eCollection 2025 Jan.
Anorectal mucosal melanoma (ARMM) is exceptionally rare, highly malignant, and characterized by a poor prognosis. We present the case of a 76-year-old woman with ARMM and recurrent gastrointestinal (GI) bleeding/anemia caused by small-bowel metastases, which was successfully managed with laparoscopic resection. ARMM is an aggressive type of cancer that has the potential to metastasize to the GI tract approximately 4.5 years after the primary diagnosis. Intussusception and GI bleed are potential complications. Small-bowel metastatic melanoma typically goes undiagnosed until autopsy and requires a multidisciplinary approach. Key treatment options include surgery and immunotherapy to improve patient outcomes.
肛管直肠黏膜黑色素瘤（ARMM）极为罕见，恶性程度高，预后较差。我们报告了一例76岁患有ARMM且因小肠转移导致反复胃肠道（GI）出血/贫血的女性病例，该病例通过腹腔镜切除术成功得到治疗。ARMM是一种侵袭性癌症，在初次诊断后约4.5年有可能转移至胃肠道。肠套叠和胃肠道出血是潜在并发症。小肠转移性黑色素瘤通常在尸检时才被诊断出来，需要多学科方法进行治疗。关键的治疗选择包括手术和免疫疗法，以改善患者预后。
