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复发性侵袭性颈椎骨母细胞瘤经放射治疗成功治愈。

Recurrent Aggressive Osteoblastoma of the Cervical Spine Successfully Treated with Radiotherapy.

作者信息

Anjos Gabriel Marques Dos, Bassan Marcos Antonio Freiberger, Gössling Gustavo, Pereira Fernando de Souza, D'Avila Rui, Izetti Patrícia

机构信息

Instituto de Oncologia Kaplan, Porto Alegre, RS, Brasil.

Hospital Ernesto Dornelles, Porto Alegre, RS, Brasil.

出版信息

Rev Bras Ortop (Sao Paulo). 2021 Nov 16;59(Suppl 2):e138-e140. doi: 10.1055/s-0041-1739300. eCollection 2024 Nov.

Abstract

Osteoblastoma is a benign disease usually treated with complete resection with curative intent, and it accounts for 14% of the benign bone tumors. A more uncommon presentation refers to a rapid growing mass known as aggressive osteoblastoma. We report the case of a young male with cervical swelling due to a progressive mass on the right side of neck with 3 months of evolution. Incisional biopsy demonstrated grade 3 osteoblastoma. A radical surgical resection was attempted, but complete resection was not feasible because of cervical invasion of C3 without spinal involvement. Despite the lack of robust data, intensity modulated radiotherapy was performed in the ipsilateral cervical region at a dose of 50 Gy in 25 fractions until November 2013. The patient is being followed up regularly without evidence of recurrence since. The so far successful treatment highlights the importance of a multidisciplinary approach for treating patients with aggressive osteoblastoma.

摘要

骨母细胞瘤是一种良性疾病,通常采用根治性完全切除进行治疗,它占良性骨肿瘤的14%。一种更罕见的表现是指一种快速生长的肿块,称为侵袭性骨母细胞瘤。我们报告一例年轻男性病例,因右侧颈部进行性肿块导致颈部肿胀,病程3个月。切开活检显示为3级骨母细胞瘤。尝试进行根治性手术切除,但由于C3颈椎受侵而无脊髓受累,无法进行完全切除。尽管缺乏有力的数据,但在2013年11月之前,对同侧颈部区域进行了调强放疗,剂量为50 Gy,分25次进行。此后该患者一直在定期随访,没有复发的迹象。迄今为止成功的治疗突出了多学科方法治疗侵袭性骨母细胞瘤患者的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c17f/11679614/82066a11141a/10-1055-s-0041-1739300-i2100150en-1.jpg

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