Janin Y, Epstein J A, Carras R, Khan A
Neurosurgery. 1981 Jan;8(1):31-8. doi: 10.1227/00006123-198101000-00007.
Benign osteoblastic lesions are rare bone tumors and they are usually divided into osteoid osteomas and benign osteoblastomas based on their biological behavior. Both lesions are prevalent in the spine, with the lamina and pedicle being involved frequently. Long diagnostic delays are frequent. Pain, the most prominent symptom, is often nocturnal and is relieved by aspirin in 30 to 40% of patients. Radicular pain occurs in 50% of the patients. The most common physical finding is tenderness in the vicinity of the lesion. Neurological abnormalities are more frequent in patients with osteoblastomas, which frequently extend into the neural canal. Tomograms are invaluable in most patients in whom plain films are normal. The bone scan is one of the most important diagnostic studies and provides an excellent means of accurately demonstrates the location and extent of the tumor. Permanent relief of pain and neurological recovery is dependent primarily on total removal of the lesion.
良性成骨细胞性病变是罕见的骨肿瘤,通常根据其生物学行为分为骨样骨瘤和良性骨母细胞瘤。这两种病变在脊柱中都很常见,椎板和椎弓根经常受累。诊断经常会出现长时间延误。疼痛是最突出的症状,通常在夜间发作,30%至40%的患者服用阿司匹林后疼痛可缓解。50%的患者会出现神经根性疼痛。最常见的体格检查发现是病变附近有压痛。骨母细胞瘤患者出现神经功能异常的情况更为常见,骨母细胞瘤常延伸至神经管。对于大多数平片正常的患者,断层扫描非常有价值。骨扫描是最重要的诊断检查之一,是准确显示肿瘤位置和范围的极佳方法。疼痛的永久缓解和神经功能恢复主要取决于病变的完全切除。